RABGGTB and TMEM25

Data Source:
BioGRID (two hybrid)

		RABGGTB	TMEM25
Description		Rab geranylgeranyltransferase subunit beta	transmembrane protein 25
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Extracellular Region Lysosome Late Endosome Plasma Membrane Integral Component Of Membrane
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	Protein Binding
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Phosphopantetheinylation Protein Prenylation Protein Geranylgeranylation Regulation Of Apoptotic Process Post-translational Protein Modification	Regulation Of Protein Stability Negative Regulation Of Excitatory Postsynaptic Potential
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		20 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA SH3GLB1 TAFA1 TMEM25 WDR4	3 interacting genes: ATXN1L GLRX3 RABGGTB
Entrez ID		5876	84866
HPRD ID		01532	11635
Ensembl ID		ENSG00000137955	ENSG00000149582
Uniprot IDs		A8KAJ2 P53611 Q6IB63	A0A024R3G8 B7Z1M8 E9PKP3 Q86YD3
PDB IDs		6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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