DDX24 and PRF1

Data Source:
HPRD (two hybrid)

		DDX24	PRF1
Description		DEAD-box helicase 24	perforin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Membrane	Extracellular Region Cytosol Plasma Membrane Membrane Integral Component Of Membrane Endosome Lumen Cytolytic Granule
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding	Calcium Ion Binding Protein Binding Wide Pore Channel Activity Identical Protein Binding
	Biological Process	RNA Metabolic Process	Immunological Synapse Formation T Cell Mediated Cytotoxicity Defense Response To Tumor Cell Immune Response To Tumor Cell Apoptotic Process Cellular Defense Response Cytolysis Protein Homooligomerization Defense Response To Virus Positive Regulation Of Killing Of Cells Of Other Organism Transmembrane Transport
Pathways
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)	Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Multiple keratinocyte cancers ( 28081215) Obesity (extreme) ( 19553259)
Interacting Genes		34 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3	8 interacting genes: CALR CYSRT1 DDX24 GZMB KRT31 NBPF19 NOTCH2NLA TRIM54
Entrez ID		57062	5551
HPRD ID		05860	01362
Ensembl ID		ENSG00000089737	ENSG00000180644
Uniprot IDs		Q9GZR7	P14222
PDB IDs
Enriched GO Terms of Interacting Partners?
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