SMYD2 and SNX11

Data Source:
BioGRID (two hybrid)

		SMYD2	SNX11
Description		SET and MYND domain containing 2	sorting nexin 11
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Endosome Membrane
	Molecular Function	RNA Polymerase II Complex Binding P53 Binding Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Heart Development Negative Regulation Of Cell Population Proliferation Histone H3-K36 Methylation Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator	Intracellular Protein Transport Vesicle Organization
Pathways		PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 27899403) Diverticular disease ( 30177863)	Body mass index ( 26426971) Generalized epilepsy ( 22949513) Triglyceride levels ( 32203549 32154731)
Interacting Genes		8 interacting genes: BTF3 BTF3L4 ESR1 H3C14 HSP90AA1 RB1 SNX11 TP53	10 interacting genes: ARL6IP1 MAJIN NECAB1 RABAC1 REEP6 RPRM SMYD1 SMYD2 YIF1A ZMYND10
Entrez ID		56950	29916
HPRD ID		15406	15410
Ensembl ID		ENSG00000143499	ENSG00000002919
Uniprot IDs		Q9NRG4	Q9Y5W9
PDB IDs		3RIB 3S7B 3S7D 3S7F 3S7J 3TG4 3TG5 4O6F 4WUY 4YND 5ARF 5ARG 5KJK 5KJL 5KJM 5KJN 5V3H 5WCG 6CBX 6CBY 6MON 6N3G	4IKB 4IKD 6KOI 6KOJ 6KOK
Enriched GO Terms of Interacting Partners?
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