YOD1 and NGRN

Data Source:
BioGRID (two hybrid)

		YOD1	NGRN
Description		YOD1 deubiquitinase	neugrin, neurite outgrowth associated
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Mitochondrion Nuclear Body Mitochondrial Membrane Intercellular Bridge Mitotic Spindle
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	RNA Binding Protein Binding RRNA Binding
	Biological Process	Macroautophagy Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination	Neuron Differentiation Positive Regulation Of Mitochondrial Translation
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Systolic blood pressure ( 28234671)	Multiple sclerosis ( 31604244)
Interacting Genes		30 interacting genes: BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 VCP ZFP57	4 interacting genes: GTF2H5 PRKAG3 TSC22D2 YOD1
Entrez ID		55432	51335
HPRD ID		10312	14825
Ensembl ID		ENSG00000180667	ENSG00000182768
Uniprot IDs		Q5VVQ6	Q9NPE2
PDB IDs		4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
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