SLC38A7 and IL10RA

Data Source:
BioGRID (two hybrid)

		SLC38A7	IL10RA
Description		solute carrier family 38 member 7	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Axon Neuronal Cell Body	Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	L-histidine Transmembrane Transporter Activity L-glutamate Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-asparagine Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity L-methionine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Amino Acid Transmembrane Transport Sodium Ion Transport Asparagine Transport Glutamine Transport Branched-chain Amino Acid Transport L-alanine Transport L-glutamate Transmembrane Transport Methionine Transport L-serine Transport L-aspartate Transmembrane Transport L-histidine Transmembrane Transport	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis
Pathways			Interleukin-10 signaling
Drugs
Diseases
GWAS		Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer ( 30648747) QT interval ( 19305408) Schizophrenia ( 25056061 29483656)	Obesity-related traits ( 23251661)
Interacting Genes		52 interacting genes: ACBD5 AMIGO1 APH1A AQP2 AQP9 ARL13B BTNL9 CLCN7 CLDN7 CLEC10A CPLX4 CREB3L3 CYB561 CYB5R3 EDA ERGIC3 ERP29 EVI2B FAM209A FCER1G FKBP7 GJA8 GJB5 GPR152 GPR42 IL10RA KIR2DL3 LMNA LY6G6C LYVE1 MMGT1 MUC1 ODF4 OPRM1 PANX1 PDCD1LG2 RNF5 SCN3B SERP2 SHISAL1 SLC10A1 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SPINT1 SSMEM1 SYPL2 TMEM237 TMEM52B TSPAN8 YIPF6	20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		55238	3587
HPRD ID		07701	00911
Ensembl ID		ENSG00000103042	ENSG00000110324
Uniprot IDs		H3BMC5 Q9NVC3	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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