SH3GLB1 and ARHGAP17

Data Source:
HPRD (in vitro)

		SH3GLB1	ARHGAP17
Description		SH3 domain containing GRB2 like, endophilin B1	Rho GTPase activating protein 17
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex	Intracellular Anatomical Structure Nucleoplasm Cytosol Plasma Membrane Bicellular Tight Junction
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding
	Biological Process	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly	Actin Filament Organization Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576	16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10
Entrez ID		51100	55114
HPRD ID		15333	12207
Ensembl ID		ENSG00000097033	ENSG00000140750
Uniprot IDs		A0A087WW40 A0A140VJU5 Q9Y371	Q68EM7
PDB IDs		6UP6 6UPN
Enriched GO Terms of Interacting Partners?
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