ATP5F1A and HSPB2

Data Source:
BioGRID (two hybrid)

		ATP5F1A	HSPB2
Description		ATP synthase F1 subunit alpha	heat shock protein family B (small) member 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration	Response To Unfolded Protein Regulation Of Catalytic Activity
Pathways		Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
Diseases
GWAS
Interacting Genes		18 interacting genes: ABCC1 AIMP1 APP ATP5F1C ATPAF2 CSNK2A1 HSD17B10 HSPB2 LINC01554 NPSR1 PTEN PTPRF SHBG SMARCB1 YWHAB YWHAG YWHAQ YWHAZ	108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335
Entrez ID		498	3316
HPRD ID		01258	03712
Ensembl ID		ENSG00000152234	ENSG00000170276
Uniprot IDs		P25705 V9HW26	A8KAH6 Q16082
PDB IDs			6F2R
Enriched GO Terms of Interacting Partners?
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