ASPA and DUSP29

Data Source:
BioGRID (two hybrid)

		ASPA	DUSP29
Description		aspartoacylase	dual specificity phosphatase 29
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GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Aspartoacylase Activity Identical Protein Binding Metal Ion Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Aspartate Catabolic Process Cellular Amino Acid Biosynthetic Process Central Nervous System Myelination Positive Regulation Of Oligodendrocyte Differentiation	Inactivation Of MAPK Activity Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Aspartate and asparagine metabolism
Drugs		Aspartic acid Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Canavan disease (CD)
GWAS		Myopia (pathological) ( 23049088)
Interacting Genes		2 interacting genes: ACY3 DUSP29	25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN
Entrez ID		443	338599
HPRD ID		02033	16846
Ensembl ID		ENSG00000108381	ENSG00000188716
Uniprot IDs		P45381 Q6FH48	Q68J44
PDB IDs		2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU	2Y96
Enriched GO Terms of Interacting Partners?
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