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MIR214 and EDC4
Data Source:
BioGRID
(unspecified method)
MIR214
EDC4
Description
microRNA 214
enhancer of mRNA decapping 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Perinuclear Region Of Cytoplasm
Extracellular Vesicle
P-body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
Protein Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Lamellipodium Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Negative Regulation Of Actin Filament Polymerization
Gene Silencing By MiRNA
Negative Regulation Of Necroptotic Process
Cellular Response To Hypoxia
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Connective Tissue Replacement
Biological_process
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways
mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
Height (
31562340
)
HDL cholesterol (
21347282
)
Metabolic syndrome (
22399527
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
92 interacting genes:
AIMP1
AIMP2
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX49
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PTBP1
PTCD3
PUF60
PUM1
PUM2
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM4B
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZC3H11A
ZFR
ZNF346
38 interacting genes:
CCL5
CDC42
EIF2AK2
FBLN1
GIT2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR122
MIR128-2
MIR141
MIR15B
MIR199A1
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR21
MIR214
MIR222
MIR29C
MIR34A
MIR34C
MIR363
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A3
MIRLET7C
MIRLET7D
MIRLET7E
SUMO2
YTHDC1
Entrez ID
406996
23644
HPRD ID
06911
Ensembl ID
ENSG00000283844
ENSG00000038358
Uniprot IDs
Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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