KRTAP12-3 and CHRNG

Data Source:
BioGRID (two hybrid)

		KRTAP12-3	CHRNG
Description		keratin associated protein 12-3	cholinergic receptor nicotinic gamma subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity
	Biological Process	Keratinization	Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Excitatory Postsynaptic Potential
Pathways		Keratinization	Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
Drugs
Diseases			Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
GWAS			Refractive error ( 23396134 32231278)
Interacting Genes		142 interacting genes: ADAMTSL3 ADAMTSL4 AGXT ALDH3B1 BCL6B BMP7 C11orf87 C22orf39 CARD10 CATSPER1 CBX2 CELF5 CHIC2 CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CYSRT1 DALRD3 DHRS1 DHX57 DNAL4 DOCK2 FASLG FBXW5 GLRX3 GNE GTF3C5 HOXA1 ITGB4 JOSD1 KPRP KRT20 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP19-7 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LIF LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MISP MOBP NBPF19 NKD1 NMU NOTCH2NLA NPDC1 NR1D2 NR4A3 NUFIP2 OTX1 OXER1 P2RX4 P2RY6 P3H3 P4HB PDE9A PDGFRB PGAP6 PHLDA1 POU4F2 PTGDS PTPMT1 R3HDM2 RSPO2 SELENOM SHFL SLC13A5 SLC15A2 SLC23A1 SPATA3 SPRY1 TCEA2 TCEANC TFAP2D TMIE TNP2 TNS2 TTPA UTP23 UXT VASN VGLL3 VSTM4 WDR25 WNT11 YY1 ZDHHC1 ZNF101 ZNF124 ZNF138 ZNF20 ZNF408 ZNF417 ZNF439 ZNF440 ZNF467 ZNF490 ZNF491 ZNF497 ZNF578 ZNF587 ZNF648 ZNF696 ZNF80 ZNF835 ZNF837 ZSCAN21	21 interacting genes: ADAMTSL4 CHRNA1 CYSRT1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP5-9 KRTAP9-3 MDFI MEOX2 NBPF19 NOTCH2NLA SGTA SNX1 SPRY2
Entrez ID		386683	1146
HPRD ID		11199	00009
Ensembl ID		ENSG00000205439	ENSG00000196811
Uniprot IDs		P60328	A0A6F7YAP6 P07510
PDB IDs
Enriched GO Terms of Interacting Partners?
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