KRTAP10-6 and NKD1

Data Source:
BioGRID (two hybrid)

		KRTAP10-6	NKD1
Description		keratin associated protein 10-6	NKD inhibitor of WNT signaling pathway 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Protein Phosphatase Type 2A Complex Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding PDZ Domain Binding
	Biological Process	Keratinization	Eye Photoreceptor Cell Differentiation Somatic Muscle Development Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Migration Involved In Somitogenic Axis Elongation Positive Regulation Of Non-canonical Wnt Signaling Pathway Via JNK Cascade Negative Regulation Of Convergent Extension Involved In Axis Elongation Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Keratinization
Drugs
Diseases
GWAS			Copper levels ( 26025379) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Systolic blood pressure ( 30224653)
Interacting Genes		73 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-5 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-9 LCE1E LCE1F LCE2C LCE2D LCE3B LCE3E LCE4A MFSD3 MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1	14 interacting genes: CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Entrez ID		386674	85407
HPRD ID		11192	08482
Ensembl ID		ENSG00000188155	ENSG00000140807
Uniprot IDs		P60371	Q969G9
PDB IDs
Enriched GO Terms of Interacting Partners?
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