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HMGN1 and PRKACG
Data Source:
BioGRID
(enzymatic study)
HMGN1
PRKACG
Description
high mobility group nucleosome binding domain 1
protein kinase cAMP-activated catalytic subunit gamma
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Nucleoplasm
Cytosol
Ciliary Base
Molecular Function
DNA Binding
Chromatin Binding
Nucleosomal DNA Binding
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
Protein Kinase A Regulatory Subunit Binding
Biological Process
Transcription-coupled Nucleotide-excision Repair
Chromatin Organization
Positive Regulation Of DNA-templated Transcription, Elongation
Stimulatory C-type Lectin Receptor Signaling Pathway
Renal Water Homeostasis
Protein Phosphorylation
Spermatogenesis
Blood Coagulation
Male Gonad Development
Protein Kinase A Signaling
Activation Of Protein Kinase A Activity
High-density Lipoprotein Particle Assembly
Cellular Response To Glucagon Stimulus
Pathways
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
PKA-mediated phosphorylation of CREB
PKA-mediated phosphorylation of key metabolic factors
Triglyceride catabolism
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
VEGFA-VEGFR2 Pathway
CREB1 phosphorylation through the activation of Adenylate Cyclase
CREB1 phosphorylation through the activation of Adenylate Cyclase
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'off' state
CD209 (DC-SIGN) signaling
MAPK6/MAPK4 signaling
RET signaling
HDL assembly
ROBO receptors bind AKAP5
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
ADORA2B mediated anti-inflammatory cytokines production
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated IL10 synthesis
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
LDL cholesterol levels (
32203549
)
Smoking status (ever vs never smokers) (
30643258
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
Interacting Genes
21 interacting genes:
CDC42
CHEK2
EP300
HMGN2
HPF1
IRF2
LIG4
MDM2
NFE2
PARP1
PPP1CC
PRKACA
PRKACG
PRKCA
RPS6KA3
RPS6KA4
RPS6KA5
SLC38A3
SPP1
TERF2
YWHAZ
5 interacting genes:
CDK17
CETP
HMGN1
TNP1
TNP2
Entrez ID
3150
5568
HPRD ID
01231
01483
Ensembl ID
ENSG00000205581
ENSG00000165059
Uniprot IDs
P05114
Q6NSG7
P22612
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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