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GPS2 and PBK
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GPS2
PBK
Description
G protein pathway suppressor 2
PDZ binding kinase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Mitochondrion
Cytosol
Transcription Repressor Complex
Nucleus
Molecular Function
Transcription Coactivator Activity
Transcription Corepressor Activity
GTPase Inhibitor Activity
Protein Binding
Cyclin Binding
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
Protein Binding
ATP Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Inactivation Of MAPK Activity
JNK Cascade
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Cholesterol Efflux
Viral Process
Regulation Of Lipid Metabolic Process
B Cell Differentiation
Negative Regulation Of Toll-like Receptor Signaling Pathway
Negative Regulation Of GTPase Activity
Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Regulation Of Fat Cell Differentiation
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of JNK Cascade
Negative Regulation Of Inflammatory Response
Negative Regulation Of B Cell Receptor Signaling Pathway
Response To Mitochondrial Depolarisation
Negative Regulation Of Protein K63-linked Ubiquitination
MAPK Cascade
Activation Of MAPK Activity
Mitotic Cell Cycle
Negative Regulation Of Protein Phosphorylation
Protein Phosphorylation
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Stress-activated MAPK Cascade
Cellular Response To UV
Negative Regulation Of Inflammatory Response
Pathways
PPARA activates gene expression
HDACs deacetylate histones
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
Drugs
Diseases
GWAS
Interacting Genes
53 interacting genes:
AKAP8L
ATF4
ATF5
BAG4
BRME1
C19orf54
CCNA1
CHD3
CNOT2
CYSRT1
DAZAP2
EP300
FAM168B
FHL5
GOLGA2
HDAC1
HDAC3
HNRNPH1
HOXA1
INTS11
KRT27
KRT31
KRT34
KRT36
KRTAP11-1
KRTAP13-2
KRTAP3-1
KRTAP3-3
KRTAP6-1
KRTAP6-2
KRTAP6-3
MAP3K7CL
NCOR1
NDOR1
NR0B2
OIP5
PBK
POU2AF1
PRMT6
PRR22
RBPMS
SESTD1
SETDB1
SMUG1
SPDL1
TBL1X
TBL1XR1
TFIP11
TP53
TP53BP2
TRIP6
UBTD2
VPS37C
19 interacting genes:
ARAF
CCNB1
CDK1
CEP126
DLG1
GPRASP1
GPS2
H2AX
LNX1
MCRS1
PTEN
RAF1
SMAD4
TERT
TP53
TRIM37
ZBTB26
ZFP64
ZNF526
Entrez ID
2874
55872
HPRD ID
11878
17822
Ensembl ID
ENSG00000132522
ENSG00000168078
Uniprot IDs
Q13227
Q96KB5
V9HWH0
PDB IDs
2L5G
5J0A
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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