FOXM1 and DCAF1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		FOXM1	DCAF1
Description		forkhead box M1	DDB1 and CUL4 associated factor 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Fibrillar Center Nucleus Nucleoplasm Cytoplasm COP9 Signalosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding	Protein Binding ATP Binding Estrogen Receptor Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity Histone Kinase Activity (H2A-T120 Specific)
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Positive Regulation Of Cell Population Proliferation Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Ras Protein Signal Transduction Regulation Of Cell Cycle Regulation Of Cell Cycle Arrest Negative Regulation Of Cell Aging Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Double-strand Break Repair	Negative Regulation Of Transcription By RNA Polymerase II Viral Process Protein Ubiquitination B Cell Differentiation V(D)J Recombination Cell Competition In A Multicellular Organism Histone H2A-T120 Phosphorylation
Pathways		Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 31562340)	Asthma ( 32296059)
Interacting Genes		18 interacting genes: BANP CCNE1 CDK1 CDK2 CDK4 CDK6 CHEK2 CREBBP DCAF1 OS9 OTUB1 SIRT1 STAT3 SUMO1 UBE2I UCHL3 USP21 ZBTB3	19 interacting genes: ATM ATR CCP110 EXO1 FOXM1 H3-3A H3-4 H3C1 HLTF KATNA1 NF2 PRKDC PYGO2 RAG1 RBX1 SAMHD1 TET2 TP53 UBE2D2
Entrez ID		2305	9730
HPRD ID		03823	11674
Ensembl ID		ENSG00000111206	ENSG00000145041
Uniprot IDs		A0A0D9SFF0 A0A2P9DTZ1 A0A2P9DTZ8 A8K591 Q08050 Q53Y49	Q9Y4B6
PDB IDs		3G73	3WA0 4CC9 4P7I 4PXW 4Z8L 5AJA 5JK7 6N45
Enriched GO Terms of Interacting Partners?
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