Wiki-Pi
About
Search
Browse
People
Updates
Search
DVL2 and U2AF2
Data Source:
HPRD
(two hybrid)
DVL2
U2AF2
Description
dishevelled segment polarity protein 2
U2 small nuclear RNA auxiliary factor 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Aggresome
Lateral Plasma Membrane
Nuclear Body
Cytoplasmic Vesicle
Apical Part Of Cell
Clathrin-coated Endocytic Vesicle
Commitment Complex
Prp19 Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
U2-type Prespliceosome
U2AF Complex
Molecular Function
Frizzled Binding
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Small GTPase Binding
Identical Protein Binding
Protein Self-association
RNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Enzyme Binding
Pre-mRNA 3'-splice Site Binding
C2H2 Zinc Finger Domain Binding
Biological Process
Neural Tube Closure
Positive Regulation Of Protein Phosphorylation
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Segment Specification
Heart Development
Convergent Extension Involved In Neural Plate Elongation
Cellular Protein Localization
Hippo Signaling
Non-canonical Wnt Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Beta-catenin Destruction Complex Disassembly
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of RNA Splicing
Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
Signaling by Hippo
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD4
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Metabolite levels (
31628463
)
Metabolite levels (small molecules and protein measures) (
27005778
)
HDL cholesterol levels (
32203549
)
Menopause (age at onset) (
26414677
)
Interacting Genes
103 interacting genes:
ABL1
AKAP9
AP1M1
AP2M1
ARHGEF39
ARR3
ARRB1
ARRB2
ATN1
AXIN1
BAG3
BAHD1
BCL6
BEND7
BYSL
CARD9
CCDC33
CPSF7
CSNK1E
CTBP2
DAAM1
DCUN1D1
DDI1
DPPA2
DYNLT1
EIF1B
ELOA2
ENKD1
FAM161A
FAM90A1
FZD4
GABARAP
GABARAPL1
GMCL2
GOLGA2
GRAP2
GRB2
HIP1
IHO1
KLHL12
LMO3
LRRK2
MAGOHB
MAP1LC3A
MCRS1
NOL12
NUP62CL
OTULIN
PARD6A
PCBD1
PLA2G12A
POLI
PPM1A
PPP1R16B
PRKAA1
PRKCA
PRKCB
PRKCG
PRPF3
PRPF31
PSMF1
RAC1
RBFOX1
RBPMS
RHOA
RHOXF2
RNF185
RNPS1
RUNX2
RUSC1
SCNM1
SMURF1
SNF8
SNIP1
SORBS3
SSX2IP
TAB1
TDP2
THAP1
TIFA
TLE5
TP53
TPM3
TRAF2
U2AF2
UBAC1
UBE2D3
UIMC1
USP5
USP9X
VANGL1
VHL
WAS
WT1
YES1
ZBTB48
ZBTB8A
ZGPAT
ZNF165
ZNF250
ZNF263
ZNF410
ZNF581
75 interacting genes:
APBB1
ATXN1
BEND7
CCAR1
CDC42
CHERP
CHIC2
CPSF7
DACH1
DDX39B
DDX6
DPPA2
DVL2
EPB41
FUBP1
GEMIN2
GLIS2
HLA-DMA
HMBOX1
IL7R
INO80B
KHDC4
KHDRBS3
LURAP1
MAP1B
MRPL15
NKAPD1
OTUB2
PHF5A
PIN1
POLR2A
PRPF3
PRPF40A
PUF60
QKI
RBFOX2
RBM11
RBM39
RBM4
RBMY1F
RBMY1J
SAP30BP
SCAF11
SF1
SF3B1
SF3B2
SF3B3
SF3B4
SF3B5
SF3B6
SMAD5
SNRPA
SRPK1
SRPK2
SRSF1
SRSF11
SRSF3
STAC3
SUGP1
SUMO2
TCERG1
TCF23
THAP1
TLE5
TOP1
U2AF1
U2AF1L5
WT1
ZNF107
ZNF526
ZNF57
ZNF71
ZNF835
ZRSR2
ZRSR2P1
Entrez ID
1856
11338
HPRD ID
03690
01872
Ensembl ID
ENSG00000004975
ENSG00000063244
Uniprot IDs
O14641
P26368
PDB IDs
2REY
3CBX
3CBY
3CBZ
3CC0
4WIP
5LNP
5SUY
5SUZ
6IW3
6JCK
1JMT
1O0P
1OPI
1U2F
2G4B
2HZC
2M0G
2U2F
2YH0
2YH1
3VAF
3VAG
3VAH
3VAI
3VAJ
3VAK
3VAL
3VAM
4FXW
4TU7
4TU8
4TU9
5EV1
5EV2
5EV3
5EV4
5W0G
5W0H
6TR0
6XLV
6XLW
6XLX
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?