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DAPK1 and GTF2F1
Data Source:
BioGRID
(pull down)
DAPK1
GTF2F1
Description
death associated protein kinase 1
general transcription factor IIF subunit 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Actin Cytoskeleton
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIF Complex
Cell Junction
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calmodulin-dependent Protein Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
GTP Binding
Syntaxin-1 Binding
Identical Protein Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
TFIIF-class Transcription Factor Complex Binding
DNA Binding
RNA Binding
Protein Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Phosphatase Activator Activity
Protein Phosphatase Binding
Protein Domain Specific Binding
Promoter-specific Chromatin Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Regulation Of Autophagy
Positive Regulation Of Autophagy
Negative Regulation Of Translation
Intracellular Signal Transduction
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Autophosphorylation
Cellular Response To Interferon-gamma
Cellular Response To Hydroperoxide
Apoptotic Signaling Pathway
Regulation Of NMDA Receptor Activity
MRNA Splicing, Via Spliceosome
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Virus
RNA Metabolic Process
Negative Regulation Of Protein Binding
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Regulation Of Catalytic Activity
Pathways
Caspase activation via Dependence Receptors in the absence of ligand
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Drugs
5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Phosphoaminophosphonic Acid-Adenylate Ester
6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE
Fostamatinib
Diseases
Bladder cancer
GWAS
Blood pressure (
24954895
)
Cognitive function (
24684796
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Height (
31562340
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Night sleep phenotypes (
27126917
)
Ovarian cancer (
30557369
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Response to gemcitabine in pancreatic cancer (
22293537
)
Interacting Genes
107 interacting genes:
ABL1
ABLIM1
AHDC1
APEX2
ARRDC1
ARRDC1-AS1
ATF6
BAG2
BAIAP2
C11orf65
CALM1
CAPRIN1
CBLB
CCDC149
CDC42EP3
CDC42SE1
CMTM4
CNTROB
DENND1C
DTWD1
DUS1L
DUX3
EPHA1
FADD
FAM107A
FAM126B
FBXL14
FBXW11
FIBP
GASK1B
GTF2F1
IKBKG
JHY
LIMA1
LIMS1
LINC02875
LMF2
LNX1
LOXL2
MAPK1
MAPK3
MCM10
MDM2
MIB1
MRGBP
MTHFD2
MYL12B
NCBP3
NECAB1
NECAP1
NR3C1
ORMDL2
PAK6
PAPSS2
PCP4
PHKG2
PIM1
PIM2
POLR2M
PPP1R14A
PPP2R1A
PPP2R2D
PPP2R5A
PRKAG2
PRR16
PWP1
RAPGEF3
RASGRP2
RCHY1
RFC5
RHBDD1
RPAP3
RPL41
SARNP
SCEL
SCRN3
SCYL1
SGK2
SH2D2A
SLAIN2
SNRPA
SNURF
SNX9
SPATS2
SPRR2G
SRSF10
STARD3
STUB1
STX1A
TAS2R60
TBC1D22B
TNFRSF1A
TPD52L1
TRADD
TRAPPC2
TTC27
TUBB4B
UNC5A
UNC5B
UNC5C
VGLL4
VN1R1
WWTR1
YWHAB
ZAP70
ZMAT4
ZMYM5
32 interacting genes:
ABL1
AHR
AR
ARNT
ATF7IP
CCNT1
CDK9
CSNK2A1
CTDP1
CTDSP1
DAPK1
FEZ1
FOS
GTF2A1
GTF2B
GTF2E1
GTF2E2
GTF2F2
GTF2H4
JUN
MAGEC1
MSX2
MYC
PARP1
POLR2A
PSMC2
PTN
SRF
TAF1
TAF11
TBP
TRIM27
Entrez ID
1612
2962
HPRD ID
02902
01803
Ensembl ID
ENSG00000196730
ENSG00000125651
Uniprot IDs
B4DHI4
P53355
Q59H88
P35269
PDB IDs
1IG1
1JKK
1JKL
1JKS
1JKT
1P4F
1WVW
1WVX
1WVY
1YR5
2W4J
2W4K
2X0G
2XUU
2XZS
2Y0A
2Y4P
2Y4V
2YAK
3DFC
3DGK
3EH9
3EHA
3F5G
3F5U
3GU4
3GU5
3GU6
3GU7
3GU8
3GUB
3ZXT
4B4L
4PF4
4TL0
4TXC
4UV0
4YO4
4YPD
5AUT
5AUU
5AUV
5AUW
5AUX
5AUY
5AUZ
5AV0
5AV1
5AV2
5AV3
5AV4
6AAR
6FHA
6FHB
6GY5
6IN4
6QMO
6QN4
1F3U
1I27
1J2X
1NHA
1ONV
2K7L
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
Enriched GO Terms of Interacting Partners
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