TRIM50 and IQUB

		TRIM50	IQUB
Description		tripartite motif containing 50	IQ motif and ubiquitin domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Acrosomal Vesicle Motile Cilium
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination	Smoothened Signaling Pathway Cilium Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	57 interacting genes: ALX4 ANAPC11 ANKRD23 BHLHB9 BLZF1 CALCOCO2 CEP70 CEP76 CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1
Entrez ID		135892	154865
HPRD ID		15566	08194
Ensembl ID		ENSG00000146755	ENSG00000164675
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	A0A024R771 Q8NA54
PDB IDs			2DAF
Enriched GO Terms of Interacting Partners?
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