TGOLN2 and AP4M1

Data Source:
HPRD (in vitro)

		TGOLN2	AP4M1
Description		trans-golgi network protein 2	adaptor related protein complex 4 subunit mu 1
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GO Annotations	Cellular Component	Nucleoplasm Endosome Endoplasmic Reticulum Lumen Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Transport Vesicle Trans-Golgi Network Transport Vesicle Clathrin-coated Vesicle Membrane	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Post-translational Protein Modification Cellular Protein Metabolic Process Membrane Organization	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Golgi Associated Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Post-translational protein phosphorylation	Lysosome Vesicle Biogenesis
Drugs
Diseases			Cerebral palsy
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2	14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		10618	9179
HPRD ID		04343	03803
Ensembl ID		ENSG00000152291	ENSG00000221838
Uniprot IDs		O43493	C9JC87 O00189
PDB IDs		6YAF	3L81 4MDR
Enriched GO Terms of Interacting Partners?
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