ARNT2 and NPAS3

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		ARNT2	NPAS3
Description		aryl hydrocarbon receptor nuclear translocator 2	neuronal PAS domain protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Response To Hypoxia In Utero Embryonic Development Regulation Of Transcription, DNA-templated Xenobiotic Metabolic Process Central Nervous System Development Brain Development Positive Regulation Of Cell Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Alcoholic chronic pancreatitis ( 28754779) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Arterial stiffness index ( 31235810) Bipolar disorder ( 31043756) Body mass index ( 26426971 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Coffee consumption ( 31046077) Colorectal or endometrial cancer ( 26621817) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) Height ( 28552196) Inflammatory biomarkers ( 22228203) Intraocular pressure ( 29617998) Lean body mass ( 28552196) Metabolite levels ( 23823483) Mitochondrial DNA levels ( 25240745) Moderate-to-late spontaneous preterm birth ( 31194736) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Night sleep phenotypes ( 27126917) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) QRS duration in Tripanosoma cruzi seropositivity ( 24324551) Schizophrenia ( 28991256) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		62 interacting genes: ADAMTSL4 AHR APP ARNT CALCOCO2 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 GOLGA2 HIF1A IKZF3 KIFC3 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 PDE4DIP PLSCR1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341	1 interacting genes: ARNT2
Entrez ID		9915	64067
HPRD ID		06915	11400
Ensembl ID		ENSG00000172379	ENSG00000151322
Uniprot IDs		Q7Z3A3 Q86TN1 Q9HBZ2 X5DQN9	Q8IXF0 X5D2Q4 X5D7M0 X5D988
PDB IDs
Enriched GO Terms of Interacting Partners?
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