RBM10 and NDEL1

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		RBM10	NDEL1
Description		RNA binding motif protein 10	nudE neurodevelopment protein 1 like 1
Image
GO Annotations	Cellular Component	Nucleus Nuclear Speck Protein-containing Complex	Kinetochore Condensed Chromosome Kinetochore Cell Nuclear Envelope Centrosome Spindle Cytosol Kinesin Complex Microtubule Synaptic Vesicle Cell Leading Edge Axon Hillock Neurofilament Cytoskeleton Central Region Of Growth Cone Axon Cytoplasm
	Molecular Function	RNA Binding Protein Binding MiRNA Binding Identical Protein Binding Metal Ion Binding	Protein Binding Microtubule Binding Identical Protein Binding Alpha-tubulin Binding Protein-containing Complex Binding Beta-tubulin Binding Oligopeptidase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Biological_process Negative Regulation Of Cell Proliferation RNA Splicing Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization	Establishment Of Mitotic Spindle Orientation Neuron Migration Inner Cell Mass Cell Proliferation Proteolysis Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Retrograde Axonal Transport Insulin Receptor Signaling Pathway Regulation Of Neuron Projection Development Cell Migration Cerebral Cortex Radially Oriented Cell Migration Central Nervous System Neuron Axonogenesis Lysosome Localization Regulation Of Intracellular Protein Transport Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Vesicle Transport Along Microtubule Positive Regulation Of Axon Regeneration Nuclear Envelope Disassembly Establishment Of Chromosome Localization Centrosome Localization Neurofilament Cytoskeleton Organization Activation Of GTPase Activity Positive Regulation Of Ruffle Assembly Neuron Projection Extension Regulation Of Microtubule Motor Activity
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		TARP syndrome
GWAS
Interacting Genes		49 interacting genes: AKAP9 ATE1 ATN1 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 MAPRE2 MEOX2 NDEL1 NIN PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12B RBM14 RBM4 RBMY1F SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF473	74 interacting genes: ACTB AIMP2 AKAP9 ANK2 APP BMI1 CASK CCDC88A CCSER1 CDK5 CENPF CEP170 CEP55 CEP63 CWF19L2 DISC1 DIXDC1 DTNB DYNC1H1 DYNC1I1 DYNLL1 FXR2 GOLGA2 IMMT KALRN KIF19 KIF2C KIF5A KIFC3 KLC4 KRT40 LUC7L2 MAGEA11 MBIP MIS18A MLLT10 MRC2 MTUS2 MYO5A NDC80 PAFAH1B1 PARD6G PKP2 PRC1 RBM10 RBM14 RBM5 RPA2 SLAIN1 SNAPC5 SNX6 SYNE1 TACC3 TRAF3IP3 TUBB USP2 XPA YWHAE YWHAG ZNF10 ZNF17 ZNF180 ZNF197 ZNF211 ZNF230 ZNF260 ZNF264 ZNF417 ZNF490 ZNF544 ZNF572 ZNF599 ZNF844 ZNF91
Entrez ID		8241	81565
HPRD ID		02095	06340
Ensembl ID		ENSG00000182872	ENSG00000166579
Uniprot IDs		A0A0S2Z4W4 A0A0S2Z4X1 P98175 Q7Z3D7	A6NIZ0 Q9GZM8
PDB IDs		2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY	2V66
Enriched GO Terms of Interacting Partners?
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