HMBOX1 and BYSL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	BYSL
Description		homeobox containing 1	bystin like
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GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Red blood cell count ( 20139978)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	67 interacting genes: AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LMNA LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TLE5 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64
Entrez ID		79618	705
HPRD ID		07964	04848
Ensembl ID		ENSG00000147421	ENSG00000112578
Uniprot IDs		D3DSU2 Q6NT76	Q13895
PDB IDs		2CUF 4J19	6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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