TYRO3 and LNX1

Number of citations of the paper that reports this interaction (PubMedID 22889411)
14

Data Source:
BioGRID (two hybrid)

		TYRO3	LNX1
Description		TYRO3 protein tyrosine kinase	ligand of numb-protein X 1
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GO Annotations	Cellular Component	Cell Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex	Cytoplasm
	Molecular Function	Virus Receptor Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol 3-kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Natural Killer Cell Differentiation Phagocytosis Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuropeptide Signaling Pathway Multicellular Organism Development Spermatogenesis Nervous System Development Phosphatidylinositol 3-kinase Signaling Cell Migration Peptidyl-tyrosine Phosphorylation Forebrain Cell Migration Platelet Activation Secretion By Cell Positive Regulation Of Kinase Activity Negative Regulation Of Toll-like Receptor Signaling Pathway Substrate Adhesion-dependent Cell Spreading Ovulation Cycle Apoptotic Cell Clearance Protein Kinase B Signaling Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Innate Immune Response Viral Entry Into Host Cell Protein Autophosphorylation Negative Regulation Of Inflammatory Response Negative Regulation Of Lymphocyte Activation Vagina Development Neuron Cellular Homeostasis Platelet Aggregation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Metabolic syndrome ( 31589552) Microalbuminuria ( 31511532) Systemic lupus erythematosus ( 24871463) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Beard thickness ( 26926045) Cervical artery dissection ( 25420145) DNA methylation (variation) ( 23725790) Heel bone mineral density ( 30598549) Height ( 28552196) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Uterine fibroids ( 30194396 31649266)
Interacting Genes		24 interacting genes: A2M APOE AXL CTDSP1 CTDSP2 ERBB2 FYN GAS6 IKBKG KLK4 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LNX1 MDFI PIK3R1 PROS1 SRC TNIP1 YES1	233 interacting genes: ABCA1 ABCB1 ABR ACAT2 ACY3 ADRA1D AGTRAP AIDA AIMP2 AKIRIN2 ALDOC ALKBH3 AMMECR1L APIP APOL4 APP ARHGAP6 ARHGEF16 ARVCF ATPAF2 ATRIP AURKB AURKC BCR BLVRA BPIFA1 C1QTNF1 CA8 CALCOCO2 CAMK2N2 CATSPERD CBY2 CCDC102B CCDC114 CCDC85B CDA CDC42EP4 CEP72 CGN CIB3 CIRBP CITED1 CLDN1 CLDN17 CLDN2 CLK2 COIL CPNE2 CTBP1 CTNND2 CTSO CUTC CXADR DAB1 DAPK1 DCTD DCUN1D5 DDX17 DEPTOR DNPEP DOCK9 DPF2 DVL3 EBF4 EHMT2 EIF4H ENOX1 EPHB3 EXOC8 FAM118A FAM124A FAM9B FBP1 FBXL12 FHL3 GAS2L2 GDI1 GIPR GJD2 GJD4 GOLPH3L GPR142 GRAP2 GRB2 GRIN1 HMBOX1 HOMEZ HSBP1 HTR2B HUNK IGSF5 IL3RA ILF3 INKA2 INSC ISCU JAK3 JOSD1 KALRN KCNA4 KCTD1 KCTD13 KCTD17 KCTD6 KHDRBS3 KLHL12 KRT15 KRTAP4-12 KRTAP4-2 KRTAP9-2 KXD1 LCLAT1 LDOC1 LGALS14 LGR6 LNX2 LRRC3B LSM2 MAGEA11 MAGEB18 MAPK9 MEMO1 METTL21A MRFAP1L1 MRPS24 MTMR9 MTUS2 MUSTN1 MVB12B NADK NAGK NCK2 NECAB2 NEK6 NKD2 NME7 NOTCH2NLA NRCAM NUDT14 NUMB NUP37 NXT2 ORMDL3 OSBP2 OSGIN1 PAFAH1B3 PAICS PBK PBLD PCBD1 PDZRN3 PDZRN4 PKDREJ PKM PKP4 PNMA1 POMGNT1 PPIA PPID PQBP1 PRR13 PTGIR PTPN11 PTS RABAC1 RAD51D RAD54B RASL11B RBMX RBMY1A1 RFPL3 ROBO3 ROPN1 RPIA RPS6KA1 RUFY4 RUVBL2 SAPCD1 SAT1 SCLT1 SDK1 SGF29 SH2D2A SHTN1 SLC6A15 SLC6A5 SNCB SNRNP25 SNRPF SOCS6 SPHKAP SRSF1 SSNA1 SSTR3 STAC2 STOML2 STRN STX5 SUV39H1 SUV39H2 TBCEL THAP7 TIFA TMEM14C TNFRSF18 TPM4 TRAF1 TRAF2 TRIM23 TRIM39 TRIM54 TRIP13 TRMT12 TSC2 TSC22D4 TSSK3 TYRO3 UBE2D2 UBE2N UBE2V2 ULK2 VCP VRK2 WAC WNT8A WWP1 ZADH2 ZBTB43 ZBTB8A ZCCHC10 ZFP64 ZNF581 ZNF593
Entrez ID		7301	84708
HPRD ID		02641	17287
Ensembl ID		ENSG00000092445	ENSG00000072201
Uniprot IDs		H0YNK6 Q06418	Q8TBB1
PDB IDs		1RHF	3B76 5H7R 5H7S
Enriched GO Terms of Interacting Partners?
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