ACTG1 and NTAQ1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ACTG1	NTAQ1
Description		actin gamma 1	N-terminal glutamine amidase 1
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Myofibril Filamentous Actin Apical Junction Complex Calyx Of Held Phagocytic Vesicle Extracellular Exosome Blood Microparticle Dense Body Schaffer Collateral - CA1 Synapse	Nucleus Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Profilin Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Angiogenesis Morphogenesis Of A Polarized Epithelium Retina Homeostasis Positive Regulation Of Gene Expression Positive Regulation Of Cell Migration Cell Junction Assembly Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Sarcomere Organization Ephrin Receptor Signaling Pathway Synaptic Vesicle Endocytosis Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Membrane Organization Platelet Aggregation Cellular Response To Interferon-gamma Positive Regulation Of Wound Healing Postsynaptic Actin Cytoskeleton Organization Tight Junction Assembly Protein Localization To Bicellular Tight Junction	Cellular Protein Modification Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Gap junction degradation Formation of annular gap junctions Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling EPH-ephrin mediated repulsion of cells Adherens junctions interactions Adherens junctions interactions Recycling pathway of L1 Recycling pathway of L1 VEGFA-VEGFR2 Pathway Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins Cell-extracellular matrix interactions RHO GTPases activate IQGAPs RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate Formins RHO GTPases Activate Formins MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Clathrin-mediated endocytosis Signaling downstream of RAS mutants FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		Copper Artenimol
Diseases
GWAS		Hand grip strength ( 29313844)
Interacting Genes		65 interacting genes: ABLIM1 ACTB ANXA5 ATF7IP BCAP31 BIN1 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK HRAS HSPB2 LGALS13 LIG4 LSP1 MAP1A MAPK6 MAPT MCPH1 MYO1A MYOC NDRG1 NR3C2 NTAQ1 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 SRPK2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WIPF1	106 interacting genes: ACTB ACTG1 AMOT AMOTL2 APIP ASL BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CBS CBY2 CCDC102B CCDC184 CDA CDR2 CEP55 COG6 COIL CRYAA CTBP1 CTH DAB1 DCTPP1 DHPS DNM2 EDARADD EIF2B1 ETV6 FTH1 GAS7 GMCL1 GMDS GNMT GOLGA2 HPRT1 HSD17B14 IKZF3 JAKMIP2 JUP KASH5 KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LMNA LNX2 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCHF10 MDFI MIF MIOS MTUS2 NAGK NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PSME3 PTS PYGM RABAC1 RBBP8 RBPMS ROPN1 RPIA SEPTIN3 SFN SIAH1 SMN1 SSX2IP STX11 TCL1A THAP1 TLE5 TMEM239 TNR TOLLIP TRAF1 TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		71	55093
HPRD ID		00017	07653
Ensembl ID		ENSG00000184009	ENSG00000156795
Uniprot IDs		P63261	A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8
PDB IDs		5JLH 6CXI 6CXJ 6G2T	3C9Q 4W79
Enriched GO Terms of Interacting Partners?
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