MLX and MNT

Number of citations of the paper that reports this interaction (PubMedID 11230181)
37

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		MLX	MNT
Description		MAX dimerization protein MLX	MAX network transcriptional repressor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nuclear Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Multicellular Organism Development Cell Aging Negative Regulation Of Cell Proliferation Regulation Of Cell Cycle Positive Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Apoptotic Signaling Pathway
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)	Autism spectrum disorder ( 26398136)
Interacting Genes		14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32	6 interacting genes: HMGB1 MAX MLX MTDH SIN3A SOX4
Entrez ID		6945	4335
HPRD ID		04278	04331
Ensembl ID		ENSG00000108788	ENSG00000070444
Uniprot IDs		Q9UH92	Q99583
PDB IDs
Enriched GO Terms of Interacting Partners?
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