HOMEZ and LRRC7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOMEZ	LRRC7
Description		homeobox and leucine zipper encoding	leucine rich repeat containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Extracellular Region Nucleoplasm Centrosome Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Specific Granule Lumen Neuron Projection Axon Initial Segment Synapse Postsynaptic Membrane Synaptic Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	MAPK Cascade Embryo Development Positive Regulation Of Neuron Projection Development Receptor Clustering Neutrophil Degranulation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Regulation Of NMDA Receptor Activity
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)
Interacting Genes		37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688	11 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A
Entrez ID		57594	57554
HPRD ID		12167	09930
Ensembl ID		ENSG00000215271	ENSG00000033122
Uniprot IDs		Q8IX15	A0A075B6E9
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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