SLC38A2 and STX11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC38A2	STX11
Description		solute carrier family 38 member 2	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Brush Border Axon Dendrite Sarcolemma Neuronal Cell Body	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Symporter Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Positive Regulation Of Gene Expression Glutamate Secretion L-serine Transport Cerebral Cortex Development Glycine Betaine Transport Alanine Transport Positive Regulation Of RNA Splicing Cellular Response To Amino Acid Starvation Cellular Response To Mechanical Stimulus Regulation Of Cellular Response To Stress Cellular Response To Arsenite(3-)	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways		Glutamate Neurotransmitter Release Cycle Amino acid transport across the plasma membrane
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Blond vs. brown/black hair color ( 30531825) Uterine fibroids ( 31649266)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		2 interacting genes: APP STX11	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		54407	8676
HPRD ID		05535	09231
Ensembl ID		ENSG00000134294	ENSG00000135604
Uniprot IDs		A0A024R0W3 Q8NHT5 Q96QD8	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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