TRIM37 and CWF19L2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM37	CWF19L2
Description		tripartite motif containing 37	CWF19 like cell cycle control factor 2
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GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm	Post-mRNA Release Spliceosomal Complex
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly	MRNA Splicing, Via Spliceosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 25644384) General cognitive ability ( 29844566) Testicular germ cell tumor ( 23666239)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		63 interacting genes: ANKRD11 APEX2 APTX ARNT2 AXIN1 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655	28 interacting genes: APP BRCA1 CALCOCO1 CALCOCO2 CARD9 CCDC136 CCDC57 FAM9B HOOK2 KRT40 LHX9 LMNA LZTS2 MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 RINT1 SF3B4 STX11 TAX1BP1 TP53BP2 TRIM27 TRIM37 TRIM54 TRIM9 VIM
Entrez ID		4591	143884
HPRD ID		05463	13102
Ensembl ID		ENSG00000108395	ENSG00000152404
Uniprot IDs		O94972	Q2TBE0
PDB IDs		3LRQ	6ID0 6ID1
Enriched GO Terms of Interacting Partners?
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