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ID3 and E2F4
Number of citations of the paper that reports this interaction (PubMedID
20211142
)
329
Data Source:
BioGRID
(two hybrid)
ID3
E2F4
Description
inhibitor of DNA binding 3, HLH protein
E2F transcription factor 4
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Chromatin
Cell
Nucleus
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Factor Complex
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Protein Domain Specific Binding
Protein Dimerization Activity
Transcription Regulator Activity
Leptomycin B Binding
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Bacterial-type RNA Polymerase Transcriptional Activator Activity, Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Sequence-specific DNA Binding
Protein Dimerization Activity
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Metanephros Development
Regulation Of DNA Replication
Multicellular Organism Development
Central Nervous System Development
Heart Development
Muscle Organ Development
Response To Wounding
Positive Regulation Of Gene Expression
Cell Differentiation
Epithelial Cell Differentiation
Notochord Development
Circadian Regulation Of Gene Expression
Odontogenesis
Positive Regulation Of Apoptotic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Myoblast Differentiation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Cellular Response To Leptomycin B
Positive Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Development
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Cycle
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Pathways
NGF-stimulated transcription
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS
Interacting Genes
37 interacting genes:
ADD1
ATF3
CBFA2T2
CDK2
CEP350
CNOT3
CSK
E2F4
ELK1
ELK4
FAM74A1
FHL2
GATA4
GNB2
GTF2A1L
HES1
ID4
IFI16
IKBKG
MLX
MYF5
MYF6
MYOD1
MYOG
PAX5
PRDM14
PUF60
RND1
RUNX1T1
SAP30
SREBF1
TCF12
TCF3
TCF4
ZNF3
ZNF408
ZNF626
29 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
Entrez ID
3399
1874
HPRD ID
02608
02806
Ensembl ID
ENSG00000117318
ENSG00000205250
Uniprot IDs
Q02535
Q16254
PDB IDs
2LFH
1CF7
5TUU
Enriched GO Terms of Interacting Partners
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