HOXC10 and NUP205

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HOXC10	NUP205
Description		homeobox C10	nucleoporin 205
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Nuclear Body	Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Nuclear Periphery Host Cell
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Skeletal System Development Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Spinal Cord Motor Neuron Cell Fate Specification Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Neuromuscular Process Negative Regulation Of Cold-induced Thermogenesis	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Nucleocytoplasmic Transport Viral Process Protein Sumoylation Viral Transcription Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Paget's disease ( 21623375) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		5 interacting genes: CDC27 EGFR ELOB NUP205 YWHAG	2 interacting genes: HOXC10 NUP93
Entrez ID		3226	23165
HPRD ID		05710	17653
Ensembl ID		ENSG00000180818	ENSG00000155561
Uniprot IDs		Q53XI4 Q9NYD6	Q92621
PDB IDs			5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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