HSPB7 and HSPB8

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		HSPB7	HSPB8
Description		heat shock protein family B (small) member 7	heat shock protein family B (small) member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cajal Body Aggresome	Intracellular Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy
Pathways			HSF1-dependent transactivation
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Arterial stiffness index ( 31235810) Erectile dysfunction ( 30583798) Systolic blood pressure ( 28739976)	Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		10 interacting genes: APP CEP76 HSPB8 PLEKHF2 PRDM14 REL SF3B4 SYCE1 TCF4 TRIM23	13 interacting genes: BAG3 CRYAB CSNK2A1 DUSP12 HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 PRKCA QRICH1 SNCA
Entrez ID		27129	26353
HPRD ID		13684	06420
Ensembl ID		ENSG00000173641	ENSG00000152137
Uniprot IDs		Q9UBY9	Q9UJY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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