RPL13A and CRP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPL13A	CRP
Description		ribosomal protein L13a	C-reactive protein
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit GAIT Complex Ribonucleoprotein Complex	Extracellular Region Extracellular Space
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome	Complement Component C1q Binding Calcium Ion Binding Protein Binding Low-density Lipoprotein Particle Binding Choline Binding Identical Protein Binding Virion Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Negative Regulation Of Translation Viral Transcription Cellular Response To Interferon-gamma Negative Regulation Of Formation Of Translation Preinitiation Complex	Acute-phase Response Inflammatory Response Complement Activation, Classical Pathway Opsonization Positive Regulation Of Gene Expression Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation By Host Of Viral Process Innate Immune Response Defense Response To Gram-positive Bacterium Negative Regulation Of Blood Vessel Diameter Regulation Of Interleukin-8 Secretion
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Classical antibody-mediated complement activation
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin Puromycin	N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRx-139
Diseases			Systemic lupus erythematosus
GWAS		Hematological and biochemical traits ( 20139978)	Blood protein levels ( 30072576 29875488 23696881) C-reactive protein ( 22492993 19567438 21647738 18439548 18439552 21196492 23844046 22939635) C-reactive protein levels ( 24763700 29403010 30388399 21300955 28548082) C-reactive protein levels in ischemic stroke ( 26718567) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Inflammatory biomarkers ( 22291609) Inflammatory biomarkers in Kawasaki disease ( 25266886) Lung cancer ( 18385676) Metabolic traits ( 19060910) Protein quantitative trait loci ( 18464913) Select biomarker traits ( 17903293)
Interacting Genes		14 interacting genes: ALDH2 ALG12 CALM1 CRP CYP2E1 ETS1 FBH1 FNTA GOLM1 MT-ND1 NOD2 PTEN STOM VTN	21 interacting genes: APCS C1QA CFH ESS2 FCGR1A FCGR2A FCGR2B FN1 GLUD1 GMPPA GP6 H1-1 H2AC16 H2AC20 LAMC3 LEP MAPK1 MAPK3 MAPK8IP2 RPL13A SNRNP70
Entrez ID		23521	1401
HPRD ID		11775	00422
Ensembl ID		ENSG00000142541	ENSG00000132693
Uniprot IDs		A0A384ME37 P40429 Q8J015	P02741
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	1B09 1CRV 1GNH 1LJ7 3L2Y 3PVN 3PVO
Enriched GO Terms of Interacting Partners?
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