ANP32B and H2BC1

Number of citations of the paper that reports this interaction (PubMedID 18039846)
12

Data Source:
BioGRID (pull down)

		ANP32B	H2BC1
Description		acidic nuclear phosphoprotein 32 family member B	H2B clustered histone 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome	Nuclear Chromosome, Telomeric Region Nucleosome Nuclear Nucleosome Nucleus Nucleoplasm Extrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding Histone Binding RNA Polymerase Binding	Molecular_function DNA Binding Histone Binding Protein Heterodimerization Activity
	Biological Process	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development	Nucleosome Assembly Nucleosome Disassembly Inflammatory Response Protein Ubiquitination Plasminogen Activation Spermatogenesis, Exchange Of Chromosomal Proteins Positive Regulation Of Binding Mononuclear Cell Migration
Pathways			Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) DNA Damage/Telomere Stress Induced Senescence HDACs deacetylate histones HATs acetylate histones HATs acetylate histones SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Ub-specific processing proteases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Deposition of new CENPA-containing nucleosomes at the centromere G2/M DNA damage checkpoint RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape E3 ubiquitin ligases ubiquitinate target proteins RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Amyloid fiber formation
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		21 interacting genes: APP CHAF1A CSNK2A1 ELAVL1 ESR1 FAM3A H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MEOX2 POLR1A SDCBP SMAD2 SMARCD1 UCHL5 XPO1	8 interacting genes: ANP32B APP CCNA1 DNTTIP2 H2AC20 HDAC3 SET USP44
Entrez ID		10541	255626
HPRD ID		09803	11024
Ensembl ID		ENSG00000136938	ENSG00000146047
Uniprot IDs		Q92688	Q96A08
PDB IDs		2ELL 2RR6	3WKJ 5GSU 5GT3 6BIY
Enriched GO Terms of Interacting Partners?
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