CDKN2D and BTG1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		CDKN2D	BTG1
Description		cyclin dependent kinase inhibitor 2D	BTG anti-proliferation factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cyclin D2-CDK4 Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding	Transcription Coregulator Activity Protein Binding Enzyme Binding Kinase Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Autophagic Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Cell Migration Negative Regulation Of Cell Growth Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Fibroblast Apoptotic Process
Pathways		Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1	FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS			Heart failure ( 20445134) Metabolite levels ( 23823483) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		22 interacting genes: APP BRCA1 BTG1 C1orf94 CDK4 CDK6 CTBP1 DMRTB1 FHL3 HSD17B14 IKZF3 INCA1 LSM3 NMI NR4A1 NR4A2 QKI SH3GLB1 SH3GLB2 TBC1D17 TEX11 TSG101	13 interacting genes: CCNA2 CDKN2D CNOT7 CNOT8 HOXB9 PRMT1 RARA RNF181 SKP2 THRA THRB TUBA1A XRCC6
Entrez ID		1032	694
HPRD ID		02957	15912
Ensembl ID		ENSG00000129355	ENSG00000133639
Uniprot IDs		A0A024R796 P55273	P62324 Q6IBC8
PDB IDs		1BD8 1BI8
Enriched GO Terms of Interacting Partners?
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