CD151 and MMP7

Number of citations of the paper that reports this interaction (PMID 16200075)
7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CD151	MMP7
Gene Name		CD151 molecule (Raph blood group)	matrix metallopeptidase 7 (matrilysin, uterine)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Protein Binding	Metalloendopeptidase Activity Zinc Ion Binding
	Biological Process	Cell Adhesion Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly T Cell Proliferation	Antibacterial Peptide Secretion Antibacterial Peptide Biosynthetic Process Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Regulation Of Cell Proliferation Response To Drug Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Cell junction organization Type I hemidesmosome assembly Collagen formation Assembly of collagen fibrils and other multimeric structures	Collagen formation Collagen degradation Activation of Matrix Metalloproteinases Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		7 interactors: GRAMD1C ITGA3 ITGA6 ITGB1 MMP7 PTGFRN RNF128	16 interactors: BCAN CD151 CD44 DCN FASLG HAPLN1 HBEGF MBP MMP1 MMP9 NGF PLG SERPINA1 SPP1 TFPI TNFSF11
Entrez ID		977	4316
HPRD ID		03763	01525
Ensembl ID		ENSG00000177697	ENSG00000137673
Uniprot IDs		E9PMR4 P48509 Q6ZNZ0	P09237
PDB IDs			1MMP 1MMQ 1MMR 2DDY 2Y6C 2Y6D
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell-substrate Adhesion Integrin-mediated Signaling Pathway Cell Adhesion Mediated By Integrin Cell-matrix Adhesion Negative Regulation Of Rho Protein Signal Transduction Regulation Of Cell-substrate Adhesion Cell-substrate Adhesion Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Leukocyte Migration Positive Regulation Of Protein Localization To Plasma Membrane Mesodermal Cell Differentiation Response To Gonadotropin Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cell Adhesion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Blood Coagulation Hemostasis Maternal Process Involved In Female Pregnancy Response To Drug Mesoderm Formation Mesoderm Morphogenesis Antibacterial Peptide Secretion Antibacterial Peptide Biosynthetic Process Regulation Of Body Fluid Levels Wound Healing Regulation Of Cell Adhesion Formation Of Primary Germ Layer Response To Wounding Negative Regulation Of Cell Projection Organization Mesoderm Development Regulation Of Collagen Catabolic Process Cell Migration Immune System Process Gastrulation Calcium-independent Cell-matrix Adhesion Cell Junction Assembly Cell Motility Cellular Response To Extracellular Stimulus Formation Of Radial Glial Scaffolds Positive Regulation Of Neuron Projection Development Skin Development Female Pregnancy Ectodermal Cell Differentiation Negative Regulation Of Signal Transduction Learning Or Memory Cell-cell Adhesion Mediated By Integrin	Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Leukocyte Migration Cell Migration Cell Motility Wound Healing Response To Wounding Immune System Process Locomotion System Development Response To Stress Movement Of Cell Or Subcellular Component Multicellular Organismal Development Organ Development Regulation Of Endopeptidase Activity Positive Regulation Of Keratinocyte Migration Anatomical Structure Development Regulation Of Peptidase Activity Blood Coagulation Hemostasis Glycosaminoglycan Catabolic Process Response To External Stimulus Response To Organic Substance Pathogenesis Response To Lipid Response To Bacterium Developmental Process Dermatan Sulfate Biosynthetic Process Regulation Of Body Fluid Levels Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process Response To Lipopolysaccharide Positive Regulation Of Bone Resorption Regulation Of Proteolysis Response To Molecule Of Bacterial Origin Tissue Development Response To Other Organism Response To Biotic Stimulus Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Axonogenesis Defense Response Inflammatory Response Response To Stimulus Positive Regulation Of Tissue Remodeling Glycosaminoglycan Metabolic Process Response To Steroid Hormone
Tagcloud ?		ca19 captured cd10 cd11b cd11c cd13 cd138 cd166 cd181 cd24 cd25 cd26 cd31 cd49d cd95 clustering concordance crc dr enabling fluorescently galectin hierarchical infiltrating panels relapse signatures til tsp	a549 a549cis a549cisdkk3 adenocarcinoma betacatenin calu1 calu1cis chemosensitivity cisplatin cisplatinresistant cisplatintreated cmyc dickkopf3 dkk3 ecadherin enhances h460 h460cis h460cisdkk3 inactivated parp proportions reactivation realize rendered retarded sb216763 seeded subline
Tagcloud (Difference) ?		ca19 captured cd10 cd11b cd11c cd13 cd138 cd166 cd181 cd24 cd25 cd26 cd31 cd49d cd95 clustering concordance crc dr enabling fluorescently galectin hierarchical infiltrating panels relapse signatures til tsp	a549 a549cis a549cisdkk3 adenocarcinoma betacatenin calu1 calu1cis chemosensitivity cisplatin cisplatinresistant cisplatintreated cmyc dickkopf3 dkk3 ecadherin enhances h460 h460cis h460cisdkk3 inactivated parp proportions reactivation realize rendered retarded sb216763 seeded subline
Tagcloud (Intersection) ?