CEP57 and KRT13

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP57	KRT13
Gene Name		centrosomal protein 57kDa	keratin 13, type I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Microtubule Microtubule Cytoskeleton	Nucleus Keratin Filament Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding	Structural Molecule Activity
	Biological Process	Protein Import Into Nucleus, Translocation G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Microtubule Anchoring Protein Homooligomerization	Cytoskeleton Organization Response To Radiation Tongue Morphogenesis Cellular Response To Retinoic Acid
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP CEP63 CTAGE5 FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MYC RALBP1 TFIP11 UIMC1	46 interactors: ABI2 ABI3 AES ALS2CR11 AMOTL2 ANKRD36BP1 APC ATP5O BLOC1S6 C1orf109 C1orf216 CCDC101 CCHCR1 CCNC CEP57 CEP57L1 EIF4E2 EXOSC5 FAM127C FARS2 FBF1 GFAP GOLGA8EP IFT20 KLC3 KLC4 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT79 KRT8 LSM2 MOS MYH1 PPP1R18 PSMB1 PSMB2 TMSB4X TRIM42 TSG101 TXLNA
Entrez ID		9702	3860
HPRD ID		16261	01016
Ensembl ID		ENSG00000166037	ENSG00000171401
Uniprot IDs		F5GYW0 Q86XR8	A1A4E9 P13646
PDB IDs		4L0R
Enriched GO Terms of Interacting Partners?		Response To Radiation Positive Regulation Of Catalytic Activity Tissue Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Spliceosomal Complex Disassembly Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Proliferation Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Response To DNA Damage Stimulus Ureteric Bud Morphogenesis Nephron Morphogenesis Developmental Process Renal Tubule Morphogenesis Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Skeletal Muscle Satellite Cell Activation Fibroblast Apoptotic Process Regulation Of Catalytic Activity Renal Tubule Development Cellular Metal Ion Homeostasis Positive Regulation Of Metabolic Process Kidney Morphogenesis Histone H2A K63-linked Deubiquitination Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Collateral Sprouting In Absence Of Injury Cellular Cation Homeostasis Cellular Ion Homeostasis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Metal Ion Homeostasis Positive Regulation Of Hydrolase Activity Cell Recognition Regulation Of Response To DNA Damage Stimulus Mesonephros Development Anatomical Structure Development Collateral Sprouting Axon Midline Choice Point Recognition Epithelium Development Regulation Of Striated Muscle Tissue Development Response To Abiotic Stimulus Notch Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Nephron Development Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Cellular Chemical Homeostasis Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis	Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Microtubule-based Process Cellular Localization Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Wnt Signaling Pathway Skin Development Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Establishment Of Localization In Cell Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Epidermis Development Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Tissue Development Positive Regulation Of Canonical Wnt Signaling Pathway Maintenance Of Protein Location In Cell Epithelium Development Microtubule-based Transport Maintenance Of Protein Location Maintenance Of Location In Cell Anatomical Structure Development Cytoskeleton-dependent Intracellular Transport Viral Process Developmental Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Macromolecule Catabolic Process Microtubule Anchoring Positive Regulation Of Wnt Signaling Pathway Keratinocyte Activation Positive Regulation Of Schwann Cell Proliferation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Opsin Transport Mitotic Cell Cycle Checkpoint Regulation Of Organelle Organization Regulation Of Cell Cycle Axon Cargo Transport Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cell Differentiation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Tagcloud ?		accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue	bisulfite chip deazaneplanocin determining dznep epigenetic h3k27me3 hsc3 hsc4 hypermethylated immunofluorescence insights keratin lys mechanistic modifications oscc osccs pathologies polycomb prc2 reactivated reportedly repressed repressive sas silenced transcriptionally trimethylation
Tagcloud (Difference) ?		accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue	bisulfite chip deazaneplanocin determining dznep epigenetic h3k27me3 hsc3 hsc4 hypermethylated immunofluorescence insights keratin lys mechanistic modifications oscc osccs pathologies polycomb prc2 reactivated reportedly repressed repressive sas silenced transcriptionally trimethylation
Tagcloud (Intersection) ?