FEZ1 and NDUFB9

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FEZ1	NDUFB9
Gene Name		fasciculation and elongation protein zeta 1 (zygin I)	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS		Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	10 interactors: FEZ1 GDF9 HAP1 IKBKAP IMMT MAGEA11 MEF2A RBBP6 SH3GL3 XRN1
Entrez ID		9638	4715
HPRD ID		09212	03264
Ensembl ID		ENSG00000149557	ENSG00000147684
Uniprot IDs		Q99689	E9PF49 Q9Y6M9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated	Cellular Response To Growth Factor Stimulus Response To Growth Factor Mitochondrion Localization Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Neurogenesis Organelle Localization Regulation Of Cell Projection Organization Regulation Of Dendrite Development Positive Regulation Of Cell Development Oocyte Growth Regulation Of Receptor Activity Positive Regulation Of Cilium Assembly ERK5 Cascade Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Secretion Regulation Of Progesterone Secretion Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Regulation Of Neurogenesis Ventricular Cardiac Myofibril Assembly Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Muscle Cell Fate Determination Positive Regulation Of Cell Proliferation In Bone Marrow Nuclear MRNA Surveillance Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Neurotrophin Signaling Pathway RNA Surveillance Regulation Of Cell Development Positive Regulation Of Cell Differentiation Cellular Macromolecule Catabolic Process RNA Metabolic Process Cellular Response To Organic Substance Hypothalamus Cell Differentiation Histone MRNA Catabolic Process Anatomical Structure Development Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Homodimerization Activity Negative Regulation Of Beta-amyloid Formation Regulation Of Cellular Component Organization Positive Regulation Of Myeloid Cell Apoptotic Process
Tagcloud ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?