RNF7 and CBFB

Number of citations of the paper that reports this interaction (PMID 23333304)
16

Data Source:
BioGRID (pull down)

		RNF7	CBFB
Gene Name		ring finger protein 7	core-binding factor, beta subunit
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cul5-RING Ubiquitin Ligase Complex	Nucleus Membrane
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Cullin Family Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Protein Ubiquitination Negative Regulation Of Apoptotic Process Protein Neddylation Response To Redox State	Osteoblast Differentiation Transcription From RNA Polymerase II Promoter Lymphocyte Differentiation Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Maturation Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784)
Protein-Protein Interactions		34 interactors: ASB2 CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS GEM GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L NFKBIA PLA2G15 TCEB1 TCEB2 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2M UBE2Q1	9 interactors: CBFA2T2 CHGB COPRS CUL5 RAB2A RNF7 RUNX1 RUNX2 RUNX3
Entrez ID		9616	865
HPRD ID		04840	00418
Ensembl ID			ENSG00000067955
Uniprot IDs		Q9UBF6	Q13951
PDB IDs		2ECL	1CL3 1E50 1H9D
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Viral Process Regulation Of DNA-templated Transcription In Response To Stress Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Proteolysis Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Protein K48-linked Ubiquitination Protein Monoubiquitination Positive Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Cell Cycle Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Apoptotic Signaling Pathway Apoptotic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Cellular Response To Stimulus Programmed Cell Death Cellular Metabolic Process Cell Death Death Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Abiotic Stimulus Proteasomal Protein Catabolic Process Cell Cycle Arrest TRIF-dependent Toll-like Receptor Signaling Pathway	Peripheral Nervous System Neuron Development Hair Follicle Morphogenesis Epidermis Morphogenesis Skin Morphogenesis Chondrocyte Differentiation Hair Follicle Development Hair Cycle Process Hair Cycle Peripheral Nervous System Development Skeletal System Development Positive Regulation Of Progesterone Secretion Regulation Of Cell Proliferation Regulation Of Progesterone Secretion Cell Maturation Regulation Of Hair Follicle Cell Proliferation Tissue Development Intrinsic Apoptotic Signaling Pathway Cartilage Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Skin Development Negative Regulation Of Granulocyte Differentiation Myeloid Progenitor Cell Differentiation Positive Regulation Of Granulocyte Differentiation Connective Tissue Development Epidermis Development Protein Neddylation Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H4-R3 Methylation Osteoblast Fate Commitment Regulation Of Female Gonad Development Regulation Of Cellular Process Epithelium Development Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Response To Redox State Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Hematopoietic Stem Cell Proliferation Apoptotic Signaling Pathway Regulation Of Odontogenesis Of Dentin-containing Tooth System Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Interferon-gamma Production Histone Arginine Methylation Regulation Of RNA Biosynthetic Process
Tagcloud ?		biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation	abl alfa aml1 amplified apl bcr characterizing clonospecific cml confirmation debate eto igh immunoglobin inv issues leukaemia mow myh1 offers opportunity presently progress purposes quantitate rearrangements residual tcr truly
Tagcloud (Difference) ?		biologically bridges consistently cul degraded e3 etoposide hect ligase ligases list nedd4 proteasome rbx2 redox ring roc2 sag scf sensitizes shortened substrates terminus transcriptionally tri ubiquitin ubiquitylated ubiquitylates ubiquitylation	abl alfa aml1 amplified apl bcr characterizing clonospecific cml confirmation debate eto igh immunoglobin inv issues leukaemia mow myh1 offers opportunity presently progress purposes quantitate rearrangements residual tcr truly
Tagcloud (Intersection) ?