MED23 and WDTC1

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		MED23	WDTC1
Gene Name		mediator complex subunit 23	WD and tetratricopeptide repeats 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Mediator Complex	Nucleus Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding	Enzyme Inhibitor Activity Protein Binding Histone Binding Histone Deacetylase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Glucose Metabolic Process Regulation Of Cell Size Protein Ubiquitination Cellular Response To Insulin Stimulus Multicellular Organism Growth Negative Regulation Of Catalytic Activity Negative Regulation Of Fatty Acid Biosynthetic Process Cellular Chemical Homeostasis
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 WDTC1	3 interactors: DDB1 MED23 MED4
Entrez ID		9439	23038
HPRD ID		05436	10307
Ensembl ID		ENSG00000112282	ENSG00000142784
Uniprot IDs		Q05DL5 Q9ULK4	Q8N5D0
PDB IDs			3I7N
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Gland Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Hormone Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Response To Lipid Response To Steroid Hormone DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Response To Organic Substance Vagina Development Uterus Development Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Female Genitalia Development Mammary Gland Epithelial Cell Proliferation Cellular Response To Lipid	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation By Virus Of Viral Protein Levels In Host Cell UV-damage Excision Repair Positive Regulation Of Viral Release From Host Cell Histone H2A Monoubiquitination Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Positive Regulation Of Viral Genome Replication Regulation Of Viral Release From Host Cell Transcription From RNA Polymerase II Promoter Interaction With Symbiont Histone Ubiquitination Androgen Receptor Signaling Pathway Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l	a8 abcc5 acvr2 biallelic crcs driver frameshift g8 glyr1 harbored intronic know microsatellite mismatch mononucleotide msh3 msi or51e2 passengers repeats rock1 suppressors t8 t9 tceb3 tgfbr2 tumourigenesis unbiased whenever
Tagcloud (Difference) ?		acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l	a8 abcc5 acvr2 biallelic crcs driver frameshift g8 glyr1 harbored intronic know microsatellite mismatch mononucleotide msh3 msi or51e2 passengers repeats rock1 suppressors t8 t9 tceb3 tgfbr2 tumourigenesis unbiased whenever
Tagcloud (Intersection) ?