ZNHIT3 and MEIS2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZNHIT3	MEIS2
Gene Name		zinc finger, HIT-type containing 3	Meis homeobox 2
Image
Gene Ontology Annotations	Cellular Component	Intracellular	Nucleus
	Molecular Function	Metal Ion Binding Thyroid Hormone Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Transcription From RNA Polymerase II Promoter Response To Mechanical Stimulus Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Growth Factor
Pathways
Drugs
Diseases
GWAS			Hyperactive-impulsive symptoms ( 18821565) Response to antipsychotic treatment ( 20195266)
Protein-Protein Interactions		13 interactors: CSNK2A2 ESR2 FAIM3 HNF4A MBNL1 MEIS2 PBX3 PITX2 PPARG RXRA THRB XRCC3 ZNF24	14 interactors: ANXA1 APP ARNT2 C1orf94 CRBN DGCR6 HOXA13 HOXA9 LINC00238 OSGIN1 PBX1 SQSTM1 TRIM25 ZNHIT3
Entrez ID		9326	4212
HPRD ID		05139	03443
Ensembl ID		ENSG00000108278	ENSG00000134138
Uniprot IDs		K7EQP1 Q15649	B3KPD8 B7Z6F6 O14770
PDB IDs		2YQQ	3K2A
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription, DNA-templated RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Response To Steroid Hormone Stimulus Nucleobase-containing Compound Metabolic Process Gene Expression Intracellular Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process System Development Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Macromolecule Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Lipid Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Lipid Negative Regulation Of Cellular Metabolic Process Response To Steroid Hormone Organ Development Peroxisome Proliferator Activated Receptor Signaling Pathway Developmental Process Response To Hormone Regulation Of Transcription, DNA-templated Epithelial Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Developmental Process Involved In Reproduction Reproductive Process	Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Biosynthetic Process Embryonic Limb Morphogenesis Regulation Of Cell Cycle Process Gland Development Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Limb Development Response To Estrogen Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Death Regulation Of G2/M Transition Of Mitotic Cell Cycle Developmental Process Regulation Of Cell Cycle G2/M Phase Transition Proximal/distal Pattern Formation Organ Development Regulation Of Transcription, DNA-templated Embryonic Forelimb Morphogenesis Positive Regulation Of Transcription, DNA-templated Reproductive Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Immune System Process Developmental Process Involved In Reproduction Regulation Of RNA Metabolic Process Forelimb Morphogenesis Sex Differentiation Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Neutrophil Clearance Prostate Gland Development Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Urogenital System Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Neutrophil Apoptotic Process Synaptic Growth At Neuromuscular Junction
Tagcloud ?		5k adenosine applies assembly bcd1 box core existence gets hsp90 isotope nop58 nucleolar nufip premature proteomic r2tp ribonucleoproteins rsa1p ruvbl scheme sequential snornas snornp snornps snu13p triphosphatase unexpected unload	accumulative aldehyde aldh1a1 blots cbfb cxcl6 devastating diras diras3 feel glaucoma homeobox identifiable immunocytochemistry meshwork negatives pitx2 protocols pursued ranking samd5 sirnas statistic sterile subtle tm tms vis
Tagcloud (Difference) ?		5k adenosine applies assembly bcd1 box core existence gets hsp90 isotope nop58 nucleolar nufip premature proteomic r2tp ribonucleoproteins rsa1p ruvbl scheme sequential snornas snornp snornps snu13p triphosphatase unexpected unload	accumulative aldehyde aldh1a1 blots cbfb cxcl6 devastating diras diras3 feel glaucoma homeobox identifiable immunocytochemistry meshwork negatives pitx2 protocols pursued ranking samd5 sirnas statistic sterile subtle tm tms vis
Tagcloud (Intersection) ?