TIFA and TNFAIP8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TIFA	TNFAIP8
Gene Name		TRAF-interacting protein with forkhead-associated domain	tumor necrosis factor, alpha-induced protein 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function	Protein Binding	Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling	Interleukin-1 Beta Production Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Defense Response To Gram-positive Bacterium
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: AP1M1 ARHGEF39 DVL2 IRAK1 LNX1 NIF3L1 NUDT18 NXF1 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF2 TRAF6 TXN2	6 interactors: INO80E MED4 PLEKHF2 PRR13 SDCBP TIFA
Entrez ID		92610	25816
HPRD ID		09835	18204
Ensembl ID
Uniprot IDs		Q96CG3	B7Z713 O95379
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of JUN Kinase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Immunoglobulin Secretion Regulation Of MAPK Cascade Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-1-mediated Signaling Pathway Positive Regulation Of T Cell Cytokine Production Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Interleukin-2 Production Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Autoubiquitination Positive Regulation Of Transferase Activity Protein Ubiquitination Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokine Production Involved In Immune Response Protein Modification By Small Protein Conjugation Regulation Of Innate Immune Response Response To External Stimulus Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway
Tagcloud ?		activate activates catalyzing conjugating consisting crude cytosolic defective exists forkhead ikk interesting ligase lys oligomeric oligomerization oligomers polyubiquitin polyubiquitination really reconstitution t2bp tak1 traf traf6 transforming ub ubc13 uev1a	affymetrix agilent asct canvac cgvhd dnjgb1 dusp1 egwas fosb generalizable genomics geo identifier illumina justify ltbr manifestation merged mmp2 mutual omnibus players repository resembles sepx1 ssc standalone subtraction uploaded
Tagcloud (Difference) ?		activate activates catalyzing conjugating consisting crude cytosolic defective exists forkhead ikk interesting ligase lys oligomeric oligomerization oligomers polyubiquitin polyubiquitination really reconstitution t2bp tak1 traf traf6 transforming ub ubc13 uev1a	affymetrix agilent asct canvac cgvhd dnjgb1 dusp1 egwas fosb generalizable genomics geo identifier illumina justify ltbr manifestation merged mmp2 mutual omnibus players repository resembles sepx1 ssc standalone subtraction uploaded
Tagcloud (Intersection) ?