CD5 and CD27

Number of citations of the paper that reports this interaction (PMID 1711157)
43

Data Source:
BioGRID (pull down)

		CD5	CD27
Gene Name		CD5 molecule	CD27 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Receptor-mediated Endocytosis Cell Recognition Cell Proliferation T Cell Costimulation Apoptotic Signaling Pathway	Cell Surface Receptor Signaling Pathway Release Of Cytoplasmic Sequestered NF-kappaB Immunoglobulin Mediated Immune Response Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088)
Protein-Protein Interactions		22 interactors: CAMK2D CBL CD2 CD247 CD27 CD4 CD6 CD72 CD79A CD79B CSNK2A1 DYNLT3 FYN HNRNPU LCK PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70	7 interactors: CD5 CD70 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2
Entrez ID		921	939
HPRD ID		01078	01723
Ensembl ID		ENSG00000110448	ENSG00000139193
Uniprot IDs		P06127	P26842
PDB IDs		2JA4 2JOP 2JP0 2OTT
Enriched GO Terms of Interacting Partners?		Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Immune System Process Regulation Of Lymphocyte Activation Regulation Of Cell Adhesion T Cell Costimulation Positive Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Signal Transduction B Cell Receptor Signaling Pathway Immune Response Signal Transduction Platelet Activation Positive Regulation Of T Cell Activation T Cell Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Adhesion Innate Immune Response Signaling Leukocyte Migration Cell Communication Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Immune Response Blood Coagulation Hemostasis Locomotion Leukocyte Activation Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Stimulus Response To Fibroblast Growth Factor Movement Of Cell Or Subcellular Component Protein Autophosphorylation Regulation Of Body Fluid Levels	Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Tumor Necrosis Factor-mediated Signaling Pathway Protein Autoubiquitination Apoptotic Signaling Pathway Immune System Process Negative Regulation Of NF-kappaB Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Toll-like Receptor Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Death Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Signal Transduction Activation Of Innate Immune Response Cell Proliferation Signaling Cell Communication Positive Regulation Of Innate Immune Response Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Immune System Process Activation-induced Cell Death Of T Cells Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Cellular Response To Stimulus Positive Regulation Of Protein Homodimerization Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Toll Signaling Pathway Cellular Response To Nitric Oxide Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Positive Regulation Of Signal Transduction
Tagcloud ?		bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	alignment augments belongs cd30 cd40 cd70 coimmunoprecipitation contains disulfide dramatically eeeg homodimerization intact ligation mediator monomers p50 p52 p65 phenomena piqed pxqxt signal traf1 traf2 traf3 trafs uses works
Tagcloud (Difference) ?		bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	alignment augments belongs cd30 cd40 cd70 coimmunoprecipitation contains disulfide dramatically eeeg homodimerization intact ligation mediator monomers p50 p52 p65 phenomena piqed pxqxt signal traf1 traf2 traf3 trafs uses works
Tagcloud (Intersection) ?