CTDP1 and NDRG2

Number of citations of the paper that reports this interaction (PMID 15670829)
17

Data Source:
HPRD (in vivo)

		CTDP1	NDRG2
Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	NDRG family member 2
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Actin Cytoskeleton Midbody Spindle Midzone	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytosol Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA-directed RNA Polymerase Activity CTD Phosphatase Activity	Molecular_function Protein Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Dephosphorylation Exit From Mitosis Gene Expression Viral Process Positive Regulation Of Viral Transcription Cell Division	Negative Regulation Of Cytokine Production Regulation Of Vascular Endothelial Growth Factor Production Wnt Signaling Pathway Substantia Nigra Development Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Platelet-derived Growth Factor Production
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Schizophrenia ( 23212062)
Protein-Protein Interactions		42 interactors: CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 HIST1H4A HIST2H2AC INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED14 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 WDR77	4 interactors: ATP1B1 CLN8 CTDP1 MOB2
Entrez ID		9150	57447
HPRD ID		05377	17630
Ensembl ID		ENSG00000060069	ENSG00000165795
Uniprot IDs		Q9Y5B0	B4DE86 Q9UN36
PDB IDs		1J2X 1ONV 2K7L	2XMQ 2XMR 2XMS
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Androgen Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription NcRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process SnRNA Processing Regulation Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Stem Cell Maintenance SnRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Positive Regulation Of Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Viral Process	Positive Regulation Of Calcium:sodium Antiporter Activity L-glutamate Uptake Involved In Synaptic Transmission Positive Regulation Of Potassium Ion Import Positive Regulation Of Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Localization To Plasma Membrane Raft Age-dependent Response To Oxidative Stress Sodium Ion Export From Cell Sodium Ion Export Somatic Motor Neuron Differentiation Cellular Potassium Ion Homeostasis L-glutamate Import Protein Transport Into Membrane Raft Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Exit From Mitosis Protein Localization To Membrane Raft Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Neurotransmitter Uptake Cellular Sodium Ion Homeostasis Relaxation Of Cardiac Muscle Membrane Repolarization Neurofilament Cytoskeleton Organization Cell Communication By Electrical Coupling Potassium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transport Neuromuscular Process Controlling Posture Amino Acid Import Positive Regulation Of Potassium Ion Transmembrane Transport Protein Transport Within Lipid Bilayer Relaxation Of Muscle Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Sodium Ion Homeostasis Potassium Ion Import Regulation Of Potassium Ion Transmembrane Transporter Activity L-glutamate Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Positive Regulation Of ATPase Activity Photoreceptor Cell Maintenance Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Social Behavior Intermediate Filament Cytoskeleton Organization Regulation Of ATPase Activity
Tagcloud ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?