PSTPIP2 and PTPN18

Number of citations of the paper that reports this interaction (PMID 9804817)
17

Data Source:
HPRD (in vivo, in vitro)

		PSTPIP2	PTPN18
Gene Name		proline-serine-threonine phosphatase interacting protein 2	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Membrane	Nucleus Cytoplasm
	Molecular Function	Actin Binding	Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Cytoskeleton Organization	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PTPN12 PTPN18 SHBG	9 interactors: ABL1 ARHGAP5 CSK ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC
Entrez ID		9050	26469
HPRD ID		06687	05961
Ensembl ID		ENSG00000152229	ENSG00000072135
Uniprot IDs		Q9H939	Q99952
PDB IDs			2OC3 4GFU
Enriched GO Terms of Interacting Partners?		Primary Spermatocyte Growth Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Dephosphorylation	Peptidyl-tyrosine Autophosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Innate Immune Response ERBB Signaling Pathway Immune Response-regulating Signaling Pathway Protein Autophosphorylation Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response Defense Response Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Wound Healing Regulation Of MAPK Cascade Immune System Process Regulation Of Immune System Process Positive Regulation Of Protein Serine/threonine Kinase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Wounding Regulation Of MAP Kinase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Cell Proliferation Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Response To Organonitrogen Compound Positive Regulation Of Phosphorylation Regulation Of Cell-cell Adhesion Axon Guidance Positive Regulation Of Protein Modification Process Peptidyl-amino Acid Modification Regulation Of Intracellular Signal Transduction Response To Oxidative Stress Central Nervous System Development Organ Development Response To Peptide Hormone Antigen Receptor-mediated Signaling Pathway Phosphorylation Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Protein Kinase Activity Regulation Of Cell Activation Cellular Response To Organonitrogen Compound
Tagcloud ?		1beta autoinflammatory autonomous carry cdc15 cmo dispensable homozygous il1alpha il1beta il1r improper inflammasome intriguingly l98p missense multifocal oligomerization osteoimmunological osteolytic osteomyelitis pathophysiology pombe precedes pyrin rescued resembling underpinnings unremitting	able al authors barcodes barcoding concept dynamic emerging et forms gives modifications nature oncogene paper pest phosphatase proteasomal rather refers regulate relay rise signals throughout trafficking translational ubiquitination wang
Tagcloud (Difference) ?		1beta autoinflammatory autonomous carry cdc15 cmo dispensable homozygous il1alpha il1beta il1r improper inflammasome intriguingly l98p missense multifocal oligomerization osteoimmunological osteolytic osteomyelitis pathophysiology pombe precedes pyrin rescued resembling underpinnings unremitting	able al authors barcodes barcoding concept dynamic emerging et forms gives modifications nature oncogene paper pest phosphatase proteasomal rather refers regulate relay rise signals throughout trafficking translational ubiquitination wang
Tagcloud (Intersection) ?