FUBP1 and PUF60

Number of citations of the paper that reports this interaction (PMID 10882074)
34

Data Source:
HPRD (two hybrid, in vivo)

		FUBP1	PUF60
Gene Name		far upstream element (FUSE) binding protein 1	poly-U binding splicing factor 60KDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Mitochondrion Golgi Apparatus Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Poly(A) RNA Binding	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Apoptotic Process RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AIMP2 CCNH CELF1 CHD3 CRMP1 GTF2H1 IMMT MAPK14 MYOC PUF60 SMN1 TLE1 VIM	30 interactors: ARL8A CACNA1A CCNC CD101 CHD3 ERG FHL2 FUBP1 HIST1H1C ID3 KIAA0907 KIAA1683 LOH12CR1 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		8880	22827
HPRD ID		10349	18051
Ensembl ID		ENSG00000162613	ENSG00000179950
Uniprot IDs		B4DT31 Q96AE4	Q9UHX1
PDB IDs		1J4W 2KXH	2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Nitrogen Compound Metabolic Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Regulation Of Gene Expression, Epigenetic Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Spliceosomal Complex Assembly Transcription Elongation From RNA Polymerase II Promoter ERBB2-ERBB3 Signaling Pathway P38MAPK Cascade Skeletal Muscle Hypertrophy Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Termination Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic RNA Splicing Positive Regulation Of Gene Expression RNA Biosynthetic Process DNA-templated Transcription, Elongation Regulation Of Metabolic Process Nucleotide-excision Repair ERBB2 Signaling Pathway Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Apoptotic Process Regulation Of Gene Expression Anatomical Structure Development Macromolecule Biosynthetic Process Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Programmed Cell Death Cell Death Death Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process	RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing RNA 3'-end Processing Negative Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Nuclear Export MRNA Transport RNA Processing Regulation Of Metabolic Process RNA Transport RNA Localization Regulation Of Gene Expression Membrane Depolarization During Action Potential Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Death Negative Regulation Of Muscle Cell Differentiation Cerebellar Molecular Layer Development Negative Regulation Of Potassium Ion Export Positive Regulation Of SUMO Transferase Activity Vestibular Nucleus Development Nucleotide-excision Repair, DNA Damage Recognition Regulation Of Heart Rate By Hormone Negative Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Cerebellum Maturation Atrial Cardiac Muscle Cell Development Musculoskeletal Movement, Spinal Reflex Action Regulation Of Apoptotic Process
Tagcloud ?		19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Difference) ?		19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Intersection) ?