CCKBR and PPP1R9B

Number of citations of the paper that reports this interaction (PMID 17464283)
18

Data Source:
HPRD (in vitro)

		CCKBR	PPP1R9B
Gene Name		cholecystokinin B receptor	protein phosphatase 1, regulatory subunit 9B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Protein Phosphatase Type 1 Complex Nucleoplasm Cytoplasm Plasma Membrane Adherens Junction Lamellipodium Filopodium Cortical Actin Cytoskeleton Ruffle Membrane Dendritic Spine Synapse
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Cholecystokinin Receptor Activity Protein Binding Gastrin Receptor Activity Type B Gastrin/cholecystokinin Receptor Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding
	Biological Process	Gastric Acid Secretion Cell Surface Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Digestion Sensory Perception Feeding Behavior Metabolic Process Cell Proliferation Positive Regulation Of Cell Proliferation Cholecystokinin Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Digestive Tract Development Gland Development	Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Protein Phosphorylation Actin Filament Organization Cell Cycle Arrest Regulation Of Exit From Mitosis RNA Splicing Dendrite Development Cell Migration Calcium-mediated Signaling Negative Regulation Of Cell Growth Regulation Of Cell Proliferation Negative Regulation Of Catalytic Activity Filopodium Assembly Regulation Of Synaptic Transmission Cellular Response To Morphine Regulation Of Opioid Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Pentagastrin
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ADRB2 ATP13A2 CCK CCKAR NTM PPP1R9B PTPN11	23 interactors: ACTA1 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 MAPK1 PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9A PRKACA RGS2 RPS6KB1 TGOLN2 TIAM1
Entrez ID		887	84687
HPRD ID		00323	04506
Ensembl ID		ENSG00000110148	ENSG00000108819
Uniprot IDs		P32239	D3DTX6 Q96SB3
PDB IDs		1L4T
Enriched GO Terms of Interacting Partners?		Neuron Development Neuron Differentiation Response To Extracellular Stimulus Generation Of Neurons Neurogenesis Neuron Projection Development Cell Development Response To External Stimulus Cell Migration Cell Differentiation Cell Motility Regulation Of Protein Phosphorylation Nervous System Development Cell Projection Organization Response To Nutrient Levels Locomotion Regulation Of Phosphorylation Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Feeding Behavior Axonogenesis Regulation Of Multicellular Organism Growth Axon Development Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Growth Cholecystokinin Signaling Pathway Regulation Of Opioid Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Neuron Projection Morphogenesis Abortive Mitotic Cell Cycle Cellular Response To Morphine Negative Regulation Of Glucocorticoid Secretion Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Developmental Process Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Neuron Migration Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Response To Isoquinoline Alkaloid Regulation Of Cell Growth By Extracellular Stimulus Response To Organonitrogen Compound Regulation Of Cellular Protein Metabolic Process Cellular Response To Manganese Ion Cell Projection Morphogenesis Positive Regulation Of Phosphorylation Cell Part Morphogenesis Positive Regulation Of Protein Modification Process Heat Generation	Energy Reserve Metabolic Process Adrenergic Receptor Signaling Pathway Regulation Of Signaling Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Regulation Of Vasoconstriction Regulation Of Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Signal Transduction Cell Surface Receptor Signaling Pathway Activation Of MAPK Activity By Adrenergic Receptor Signaling Pathway Signaling Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Cell Communication Negative Regulation Of Signaling Regulation Of MAPK Cascade Generation Of Precursor Metabolites And Energy Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Epidermal Growth Factor-activated Receptor Transactivation By G-protein Coupled Receptor Signaling Pathway Regulation Of Hormone Secretion Triglyceride Catabolic Process Positive Regulation Of MAPK Cascade Regulation Of Phosphorylation Receptor Transactivation Acylglycerol Catabolic Process Developmental Process Negative Regulation Of Epinephrine Secretion Response To External Stimulus Regulation Of Kinase Activity Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Glycogen Catabolic Process G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Norepinephrine Secretion Response To Organic Substance Response To Stimulus Positive Regulation Of Signal Transduction Muscle System Process Regulation Of Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cellular Localization Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity System Development Anatomical Structure Development Regulation Of Norepinephrine Secretion Negative Regulation Of Signal Transduction Response To Abiotic Stimulus
Tagcloud ?		13qter 9p acp5 cholecystokinin chro chromosomes converter eleven ends fall39 glycoprotein integrin itgam itgbeta2 linkage mapping mu opioid oprm1 pc1 pellucida rbp3 retinol rflp rnr1 ssc swine zona zp1	accn1 ago arises cgg description disturbed eef1a2 fmr1 fmrp fragile gabrd hes1 inherited intelligence interactive lending lymphoblastoid lymphoblasts males microarrays morphogenesis neurodevelopment overrepresentation retardation syndrome transcriptome trinucleotide unc13b untranslated
Tagcloud (Difference) ?		13qter 9p acp5 cholecystokinin chro chromosomes converter eleven ends fall39 glycoprotein integrin itgam itgbeta2 linkage mapping mu opioid oprm1 pc1 pellucida rbp3 retinol rflp rnr1 ssc swine zona zp1	accn1 ago arises cgg description disturbed eef1a2 fmr1 fmrp fragile gabrd hes1 inherited intelligence interactive lending lymphoblastoid lymphoblasts males microarrays morphogenesis neurodevelopment overrepresentation retardation syndrome transcriptome trinucleotide unc13b untranslated
Tagcloud (Intersection) ?