SNX4 and HIVEP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SNX4	HIVEP1
Gene Name		sorting nexin 4	human immunodeficiency virus type I enhancer binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane Extrinsic Component Of Membrane SNARE Complex Early Endosome Membrane Protein Complex	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Transport Vesicle Organization Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Alcohol and nictotine co-dependence ( 22488850)
Protein-Protein Interactions		15 interactors: AGK ARL6IP1 ATP6V0A1 BIN1 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SNX2 SNX6 SUPT5H	35 interactors: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A DNAJA1 EMG1 GAA GSDMB HPD HRSP12 HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 STAT3 TMEM176A
Entrez ID		8723	3096
HPRD ID		09334	01925
Ensembl ID		ENSG00000114520	ENSG00000095951
Uniprot IDs		O95219	P15822
PDB IDs			1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?		Metanephric Glomerular Capillary Formation Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA Metabolic Process Positive Regulation Of Phospholipase C Activity Glomerular Capillary Formation Protein Autophosphorylation Positive Regulation Of DNA Replication Metanephric Glomerulus Vasculature Development Positive Regulation Of Phospholipase Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Peptidyl-tyrosine Phosphorylation Metanephric Glomerulus Development Glomerulus Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of DNA Replication Positive Regulation Of ERK1 And ERK2 Cascade Retina Vasculature Development In Camera-type Eye Glomerulus Vasculature Development Cardiac Myofibril Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Response To Platelet-derived Growth Factor Regulation Of Kinase Activity Digestive System Development Regulation Of Reactive Oxygen Species Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Fibroblast Growth Factor Adrenal Gland Development Metanephric Nephron Development Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Regulation Of Catalytic Activity	Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cell Death Regulation Of Cell Death Neurotrophin Signaling Pathway Regulation Of Signaling Regulation Of Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stress Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Growth Regulation Of Phosphorylation Glucose Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cell Death Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Hexose Metabolic Process Positive Regulation Of Organelle Organization
Tagcloud ?			16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Difference) ?			16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Intersection) ?