SERPINH1 and KLF13

Number of citations of the paper that reports this interaction (PMID 11748222)
25

Data Source:
HPRD (in vitro, in vivo)

		SERPINH1	KLF13
Gene Name		serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	Kruppel-like factor 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Collagen Binding Poly(A) RNA Binding Unfolded Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Transcription From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Collagen formation Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Height ( 20881960 22021425)
Protein-Protein Interactions		17 interactors: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 HIST1H1B HMP19 KLF13 PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	9 interactors: CREBBP EP300 KAT2B PCBD1 PRPF4B SERPINH1 SIN3A SREBF1 SREBF2
Entrez ID		871	51621
HPRD ID		02968	05620
Ensembl ID		ENSG00000149257	ENSG00000169926
Uniprot IDs		A8K259 P50454	Q9Y2Y9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Replication DNA-templated Transcription, Initiation Regulation Of Cell Proliferation Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Proliferation Regulation Of DNA Replication Cell Maturation Regulation Of Cellular Component Organization Transcription Initiation From RNA Polymerase II Promoter Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cellular Metabolic Process Brown Fat Cell Differentiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Replication Fork Arrest Response To Diuretic Amylopectin Biosynthetic Process Single Organism Reproductive Process Regulation Of Cellular Process Chromatin Organization Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E DNA-templated Transcription, Elongation Reproductive Process Apoptotic Signaling Pathway Regulation Of Cell Growth Brain Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Protein Stabilization Macromolecule Biosynthetic Process Head Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Multicellular Organism Reproduction Steroid Hormone Mediated Signaling Pathway Meiosis I Membrane Organization DNA-dependent DNA Replication Cellular Response To Oxygen Levels Transcription From RNA Polymerase II Promoter Female Gonad Development Regulation Of Gene Expression Signal Transduction By P53 Class Mediator Development Of Primary Female Sexual Characteristics Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation	N-terminal Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Gene Expression Rhythmic Process Positive Regulation Of Transcription, DNA-templated N-terminal Protein Amino Acid Modification Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated Macromolecule Biosynthetic Process RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Notch Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromatin Modification Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Cellular Response To Heat Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Response To Organic Substance Chromatin Organization Peptidyl-lysine Modification Regulation Of Binding Cellular Response To Stress Regulation Of Protein Deacetylation Regulation Of Transcription, DNA-templated
Tagcloud ?		act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe	advantage cardiomyocyte cardiomyocytes cognate congenital continues dissection ease elucidating embryos finger gata4 genetically holds inability manipulating manipulations modifier morphogenesis multidisciplinary owing promise regenerative requirement starting took unlike xenopus
Tagcloud (Difference) ?		act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe	advantage cardiomyocyte cardiomyocytes cognate congenital continues dissection ease elucidating embryos finger gata4 genetically holds inability manipulating manipulations modifier morphogenesis multidisciplinary owing promise regenerative requirement starting took unlike xenopus
Tagcloud (Intersection) ?