PLA2G4C and S100A10

Number of citations of the paper that reports this interaction (PMID 9202034)
13

Data Source:
BioGRID (pull down)

		PLA2G4C	S100A10
Gene Name		phospholipase A2, group IVC (cytosolic, calcium-independent)	S100 calcium binding protein A10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Cell Cortex Membrane	Extrinsic Component Of Plasma Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Phospholipid Binding Calcium-independent Phospholipase A2 Activity	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Phospholipid Metabolic Process Inflammatory Response Parturition Arachidonic Acid Metabolic Process Intracellular Signal Transduction Phosphatidylinositol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process Glycerophospholipid Catabolic Process	Membrane Raft Assembly Membrane Budding Positive Regulation Of Rac GTPase Activity Positive Regulation Of Binding Protein Heterotetramerization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Acyl chain remodelling of PE Hydrolysis of LPC Metabolism of lipids and lipoproteins Acyl chain remodelling of PI Phospholipid metabolism Glycerophospholipid biosynthesis Acyl chain remodelling of PC Hydrolysis of LPE	Dissolution of Fibrin Clot Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP S100A10	13 interactors: ANXA2 ANXA7 BAD CDK16 COPS6 CTSB FSHR KCNK3 PLA2G4C PLG SETDB1 TRPV5 TRPV6
Entrez ID		8605	6281
HPRD ID		04673	00232
Ensembl ID		ENSG00000105499	ENSG00000197747
Uniprot IDs		Q9UP65	P60903
PDB IDs			1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
Enriched GO Terms of Interacting Partners?		Regulation Of Binding Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Membrane Raft Assembly Protein Heterotetramerization Regulation Of Cell Development Cellular Copper Ion Homeostasis Membrane Raft Organization Membrane Assembly Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Hydrolase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Membrane Biogenesis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Substrate Adhesion-dependent Cell Spreading Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Focal Adhesion Assembly Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Catalytic Activity Axon Cargo Transport Mating Neuromuscular Junction Development Regulation Of Cell Differentiation Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Rac GTPase Activity Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Junction Assembly Regulation Of Protein Tyrosine Kinase Activity	Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Cellular Homeostasis Reproductive Process Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Calcium Ion Homeostasis Homeostatic Process Calcium Ion Homeostasis Cellular Response To Chromate Response To Metal Ion Extracellular Matrix Organization Extracellular Structure Organization Chemical Homeostasis Regulation Of Blood Coagulation Positive Regulation Of Mitochondrial Membrane Potential Suppression By Virus Of Host Apoptotic Process Extracellular Matrix Disassembly Cellular Metal Ion Homeostasis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Anatomical Structure Development Protein Tetramerization Cellular Cation Homeostasis Mononuclear Cell Migration Cellular Response To Oxygen Levels Cellular Ion Homeostasis Response To Calcium Ion Catabolic Process Metal Ion Homeostasis Regulation Of Wound Healing Response To Inorganic Substance Reproductive Structure Development Reproductive System Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Apoptotic Process By Virus Glucose Catabolic Process Positive Regulation Of Fibrinolysis Cellular Response To Inorganic Substance Positive Regulation Of Type B Pancreatic Cell Development Follicle-stimulating Hormone Signaling Pathway Cellular Chemical Homeostasis Single Organism Reproductive Process Establishment Of Localization In Cell Organ Development System Development Developmental Process Ion Homeostasis Positive Regulation Of Glucokinase Activity
Tagcloud ?		19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 q13 radio rpl18 srm zin	annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions
Tagcloud (Difference) ?		19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 q13 radio rpl18 srm zin	annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions
Tagcloud (Intersection) ?