RGS20 and LCE2D

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RGS20	LCE2D
Gene Name		regulator of G-protein signaling 20	late cornified envelope 2D
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Keratinization
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16	14 interactors: ADAMTSL4 EFEMP2 GLRX3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 NOTCH2NL OTX1 PLSCR1 RGS20 SPRY1 SPRY2 SUMO1P1
Entrez ID		8601	353141
HPRD ID		06225	17261
Ensembl ID		ENSG00000147509	ENSG00000187223
Uniprot IDs		H9NIM5 O76081	Q5TA82
PDB IDs
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis	Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Branch Elongation Of An Epithelium Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Spindle Localization Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Inner Ear Morphogenesis Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity Ear Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Developmental Growth Involved In Morphogenesis Negative Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Establishment Or Maintenance Of Cell Polarity Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Phosphatidylserine Biosynthetic Process Inner Ear Development Regulation Of ERK1 And ERK2 Cascade Diencephalon Morphogenesis Branching Morphogenesis Of An Epithelial Tube Regulation Of GTPase Activity Negative Regulation Of Protein Kinase Activity Lung Growth Negative Regulation Of Kinase Activity Ear Development Morphogenesis Of A Branching Epithelium Lung Development Morphogenesis Of A Branching Structure Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
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