STX7 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX7	STX4
Gene Name		syntaxin 7	syntaxin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Tertiary Granule	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ENTPD2 MAPK6 NAPA SNAP29 STX4 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		8417	6810
HPRD ID		04449	01722
Ensembl ID			ENSG00000103496
Uniprot IDs		O15400	A8MXY0 B7Z425 Q12846
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Protein Transport Establishment Of Protein Localization Vesicle Organization Protein Localization Intracellular Protein Transport Establishment Of Localization In Cell Vesicle-mediated Transport Intracellular Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Golgi Vesicle Transport Membrane Organization Cellular Protein Localization SNARE Complex Assembly Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Vesicle-mediated Transport Endosomal Transport Secretion By Cell Positive Regulation Of Regulated Secretory Pathway Secretion Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Exocytosis Regulation Of Regulated Secretory Pathway Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Cellular Component Organization Transport Regulation Of Protein Localization Positive Regulation Of Exocytosis Regulation Of SNARE Complex Assembly Autophagic Vacuole Fusion Vesicle Fusion With Golgi Apparatus Regulation Of Cellular Localization Vacuolar Transport Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Docking Positive Regulation Of Mast Cell Degranulation Interaction With Host Positive Regulation Of Hormone Secretion Positive Regulation Of Mast Cell Activation Cellular Protein Complex Assembly Organelle Organization Regulation Of Mast Cell Degranulation Endosome To Lysosome Transport	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx6 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vesicle vti1b	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized view vps26a
Tagcloud (Intersection) ?		stx4 vamp3